对呋喃唑酮的接触性过敏

Contact allergy to furazolidone.

作者信息

de Groot A C, Conemans J M

机构信息

Department of Dermatology, Carolus Hospital, BD's-Hertogenbosch, The Netherlands.

出版信息

Contact Dermatitis. 1990 Apr;22(4):202-5. doi: 10.1111/j.1600-0536.1990.tb01567.x.

DOI:10.1111/j.1600-0536.1990.tb01567.x

PMID:2140751

Abstract

A case of occupational contact allergy to furazolidone, used as an animal feed additive and as an antimicrobial drug in veterinary medicine, is described. The patient did not react to furazolidone 2% pet. Using PEG-400 and alcohol as patch test vehicles resulted in positive patch test reactions. No cross-reactions were observed to other nitrofuran derivatives (nitrofurazone, nitrofurantoin) or to furfural. The literature on contact allergy to nitrofurans is reviewed.

摘要

本文描述了一例职业性接触性过敏病例，过敏原为用作动物饲料添加剂和兽用抗菌药物的呋喃唑酮。患者对2%的呋喃唑酮凡士林制剂无反应。使用聚乙二醇400和酒精作为斑贴试验载体时，斑贴试验反应呈阳性。未观察到对其他硝基呋喃衍生物（呋喃西林、呋喃妥因）或糠醛的交叉反应。本文对硝基呋喃接触性过敏的文献进行了综述。