S. CHAKRABARTI, M.D., MRC Psych., Assistant Professor, Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh -160012.
Indian J Psychiatry. 2000 Jan;42(1):29-33.
In an exercise carried out to ascertain adequacy of antidepressant treatment, seventy case notes of patients of depression on continuation treatment with antidepressants were scanned. Antidepressants had been used universally. TCAs were the most commonly used drugs, although Fluoxetine had also been used quite frequently. Continuation treatment was found to be deficient in over a third (n=24; 34 %) of the cases, on either of the two parameters i. e. dose of drugs or duration of treatment. The outcome was poorer in those treated inadequately. The reasons for this 'treatment gap' need to be explored. Similar studies need to be conducted in other settings. Education of all clinicians about these central issues of antidepressant treatment is essential.
在一项旨在确定抗抑郁治疗是否充分的研究中,对 70 例正在接受抗抑郁药维持治疗的抑郁症患者的病历进行了扫描。所有患者均使用抗抑郁药治疗。TCAs 是最常用的药物,尽管氟西汀的使用也相当频繁。结果发现,超过三分之一(n=24;34%)的病例在药物剂量或治疗持续时间这两个参数中的任何一个上都存在治疗不足的情况。治疗不充分的患者预后更差。需要探讨造成这种“治疗差距”的原因。需要在其他环境中开展类似的研究。对所有临床医生进行有关抗抑郁治疗这些核心问题的教育至关重要。