内源性抑郁症患者对电抽搐治疗反应的临床预测因子。
Clinical variables as predictors of response to electroconvulsive therapy in endogenous depression.
机构信息
NITIN GUPTA, MD., Assistant Professor, Department of Psychiatry, PGIMER, Chandigarh-160012.
出版信息
Indian J Psychiatry. 2000 Jan;42(1):60-5.
There is lack of consensus on the clinical variables that predict response to ECT. Identification of clinical variables could help in predicting the type of response before the start of ECT Therefore, a prospective study on 22 patients of severe depression, some of whom were drug-naive and others drug free at time of ECT was undertaken. A maximum of six ECT were administered with a prior definition of 'good response' (60% or greater reduction in Hamilton Depression Rating Scale scores) Results showed that three clinical variables could distinguish between good responders and poor responders Hence, response to ECT was associated with the duration of past depressive episodes, suicidal thoughts and somatic symptoms.
目前，针对哪些临床变量可预测电休克治疗（ECT）的疗效，尚未达成共识。如果能识别出这些临床变量，或许有助于在 ECT 治疗开始前预测患者的反应类型。因此，我们对 22 例重度抑郁症患者进行了一项前瞻性研究，其中一些患者在 ECT 治疗时为初发，另一些患者在 ECT 治疗时已经停药。患者接受了最多 6 次 ECT 治疗，预先定义“良好反应”（汉密尔顿抑郁量表评分降低 60%或以上）。结果表明，有 3 个临床变量可区分良好反应者和不良反应者。因此，ECT 的疗效与既往抑郁发作持续时间、自杀意念和躯体症状有关。
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