RAMANAND SATAPATHY, MD., Assistant Professor of Psychiatry, Andhra Medical College and Government Hospital for Mental Care, Visakhapatnam-530 023.
Indian J Psychiatry. 2000 Oct;42(4):427-33.
Neuropsychiatric disorders are common both secondary to the complications of immune suppression and as direct effects of HIV on the brain. A high prevalence of psychiatric disorder is reported both in physically asymptomatic and symptomatic persons. A thorough search was made in MEDLAR for the research literature available in the field of neuropsychiatric manifestations of AIDS. There is paucity of literature particularly in India and to be more specific in asymptomatic AIDS individuals, hence this study is intended to fill up the lacuna. The findings of this study show that the prevalence rate of psychiatric manifestations is 90% in HIV positive individuals and 33% in HIV negative group. This rate is significantly high though they are not suffering with physically disabling symptoms. So, the coping mechanisms and defence mechanisms in an individual who acquired HIV infection should be assessed and the significance of counselling before screening, plays a major role in the management of asymptomatic positive and negative individual.
神经精神障碍在继发于免疫抑制的并发症和 HIV 对大脑的直接影响方面都很常见。在无症状和有症状的人群中，都有很高的精神疾病患病率报告。在 MEDLAR 中对艾滋病神经精神表现领域的研究文献进行了全面搜索。特别是在印度，文献非常匮乏，更具体地说，在无症状艾滋病个体中，因此本研究旨在填补空白。本研究的结果表明，在 HIV 阳性个体中，精神表现的患病率为 90%，在 HIV 阴性组中为 33%。尽管他们没有身体残疾症状，但这一比率非常高。因此，应该评估个体在获得 HIV 感染后的应对机制和防御机制，并且在筛查前进行咨询的意义在管理无症状阳性和阴性个体方面起着重要作用。
