土耳其多发性硬化症队列中亲属银屑病的高发病率。
High frequency of psoriasis in relatives in a Turkish multiple sclerosis cohort.
作者信息
Dogan Sibel, Atakan Nilgün, Kurne Asli, Karabudak Rana
机构信息
Department of Dermatology, Hacettepe University, Faculty of Medicine, Ankara, Turkey.
出版信息
Skinmed. 2011 Jan-Feb;9(1):11-3.
Psoriasis was recently accepted as an autoimmune T cell-mediated disease. Various autoimmune disease associations for psoriasis have been defined, including multiple sclerosis, a model autoimmune demyelinating neurologic disorder. In this study, the familial frequency of psoriasis in a Turkish multiple sclerosis cohort was investigated, and a higher frequency of psoriasis was found, supporting the presence of a complex background of autoimmunity underlying psoriasis.
银屑病最近被认定为一种自身免疫性T细胞介导的疾病。已经确定了银屑病与多种自身免疫性疾病的关联，包括多发性硬化症，一种典型的自身免疫性脱髓鞘神经疾病。在本研究中，调查了土耳其多发性硬化症队列中银屑病的家族发病率，发现银屑病的发病率较高，这支持了银屑病背后存在复杂自身免疫背景的观点。
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