Maes H, Vingerhoets F, Berney A
Faculté de biologie et médecine, Université de Lausanne, Rue du Bugnon 21, 1015 Lausanne.
Rev Med Suisse. 2011 Feb 16;7(282):385-8.
Subthalamic nucleus deep brain stimulation (STN-DBS) is a recognized treatment for advanced and severe forms of Parkinson's Disease. The procedure improves motor signs and often allows a reduction of the medication. The impact of the procedure on cognitive and neuropsychiatric signs of the disease is more debated and there is an international consensus for the need of a multidisciplinary evaluation of patients undergoing such programs, including a neuropsychiatric assessment. We present a review of the literature as well as the experience at our centre focused on the short and long term outcome on mood following STN-DBS.
丘脑底核深部脑刺激术（STN-DBS）是治疗晚期和严重帕金森病的一种公认疗法。该手术可改善运动症状，且常常能减少药物用量。该手术对疾病认知和神经精神症状的影响存在更多争议，国际上达成共识，认为需要对接受此类治疗方案的患者进行多学科评估，包括神经精神评估。我们对相关文献以及我们中心的经验进行了综述，重点关注STN-DBS术后情绪的短期和长期结果。
