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[接受丘脑底核深部脑刺激治疗的帕金森病患者的心境障碍患病率]

[Prevalence of mood disorders in Parkinson's disease patients treated with subthalamic nucleus deep brain stimulation].

作者信息

Maes H, Vingerhoets F, Berney A

机构信息

Faculté de biologie et médecine, Université de Lausanne, Rue du Bugnon 21, 1015 Lausanne.

出版信息

Rev Med Suisse. 2011 Feb 16;7(282):385-8.

Abstract

Subthalamic nucleus deep brain stimulation (STN-DBS) is a recognized treatment for advanced and severe forms of Parkinson's Disease. The procedure improves motor signs and often allows a reduction of the medication. The impact of the procedure on cognitive and neuropsychiatric signs of the disease is more debated and there is an international consensus for the need of a multidisciplinary evaluation of patients undergoing such programs, including a neuropsychiatric assessment. We present a review of the literature as well as the experience at our centre focused on the short and long term outcome on mood following STN-DBS.

摘要

丘脑底核深部脑刺激术(STN-DBS)是治疗晚期和严重帕金森病的一种公认疗法。该手术可改善运动症状,且常常能减少药物用量。该手术对疾病认知和神经精神症状的影响存在更多争议,国际上达成共识,认为需要对接受此类治疗方案的患者进行多学科评估,包括神经精神评估。我们对相关文献以及我们中心的经验进行了综述,重点关注STN-DBS术后情绪的短期和长期结果。

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