帕金森病患者接受喹硫平治疗后出现新发精神病的长期影响。
A Long Term Effects of a New Onset Psychosis after DBS Treated with Quetiapine in a Patient with Parkinson's Disease.
机构信息
Rehabilitation Unit for the Acquired Neuropsychological Disorders, "E. Medea" Scientific Institute Conegliano-Pieve di Soligo Research Center, Pieve di Soligo, Italy.
Department of Mental Health ULSS 7, Pieve di Soligo, Italy. ; Department of Neuroscience, University of Padoua, Padoua, Italy.
出版信息
Psychiatry Investig. 2015 Jan;12(1):146-9. doi: 10.4306/pi.2015.12.1.146. Epub 2015 Jan 12.
Abstract
Deep Brain Stimulation represents a therapeutic option for PD patients. In this paper, we present and discuss a case of acute delirium and psychosis manifesting after DBS in a 58-years-old man affected by Parkinson's Disease. We highlight the importance of an exhaustive psychiatric evaluation in candidates for DBS and we underline the severity and non-reversibility of some adverse events associated with the implantation, suggesting the use of Quetiapine in the management of these effects. Acute psychosis may be listed as a potential severe adverse event associated with DBS, even in patients without a clear cut previous history of psychiatric disorders.
摘要
深部脑刺激代表了 PD 患者的一种治疗选择。在本文中，我们介绍并讨论了一例 58 岁男性帕金森病患者在接受 DBS 后出现的急性谵妄和精神病。我们强调了对 DBS 候选者进行详尽的精神评估的重要性，并强调了与植入相关的一些不良事件的严重性和不可逆转性，提示使用喹硫平来管理这些影响。急性精神病可能被列为与 DBS 相关的潜在严重不良事件，即使是在没有明显既往精神疾病史的患者中也是如此。
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本文引用的文献
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