Department of Urology, University of Heidelberg, Heidelberg, Germany.
J Urol. 2011 May;185(5):1751-5. doi: 10.1016/j.juro.2010.12.045. Epub 2011 Mar 21.
Selective percutaneous transarterial embolization has proved to be effective, safe treatment for posttraumatic renal hemorrhage but inefficacious procedures often lead to nephrectomy. Thus, the success rate of transarterial embolization should be maximized.
We retrospectively investigated the clinical success rate of transarterial embolization for posttraumatic bleeding. Study inclusion criteria were imaging evidence and clinical signs of hemorrhage or a hemoglobin decrease of more than 2 gm/dl in urological cases. We excluded spontaneous bleeding from analysis.
A total of 21 patients with a median age of 66 years (range 12 to 78) met study inclusion criteria. Etiology was blunt trauma in 3 cases (14%), stab wound in 1 (5%) and an iatrogenic cause in 17 (81%). In 2 patients an active bleeding site could not be detected during selective angiography. Transarterial embolization was done in 19 patients and led to primary clinical success in 12 (63%), including 2 with grade V parenchymal injury. In 6 of 7 cases (86%) in which primary treatment failed transarterial embolization was repeated. It resulted in clinical success in 4 of 6 patients (67%) with equal efficiency (p =1). Three patients (16%) who could not be sufficiently treated with transarterial embolization underwent nephrectomy.
When conservative measures fail and clinical symptoms or a relevant hemoglobin decrease occur, transarterial embolization should be considered. Since the success rate is equally high for initial and repeat interventions, re-intervention is justified when the clinical course allows.
选择性经动脉栓塞已被证明是治疗创伤后肾出血的有效、安全的方法,但无效的治疗往往导致肾切除。因此,应最大限度地提高经动脉栓塞的成功率。
我们回顾性研究了经动脉栓塞治疗创伤后出血的临床成功率。研究纳入标准为影像学证据和临床出血迹象或泌尿科病例血红蛋白下降超过 2 克/分升。我们排除了自发性出血的分析。
共有 21 名患者符合研究纳入标准,中位年龄为 66 岁(范围 12 至 78 岁)。病因是 3 例(14%)钝性创伤、1 例(5%)刺伤和 17 例(81%)医源性损伤。在 2 例患者中,选择性血管造影未能检测到活跃的出血部位。19 例患者进行了经动脉栓塞治疗,12 例(63%)患者获得了主要临床成功,包括 2 例 5 级实质损伤患者。在 7 例(86%)首次治疗失败的患者中,重复进行了经动脉栓塞治疗。在 4 例患者中(67%)获得了临床成功,其效果相同(p=1)。3 例(16%)经动脉栓塞治疗不能充分治疗的患者行肾切除术。
当保守治疗失败且出现临床症状或相关血红蛋白下降时,应考虑经动脉栓塞治疗。由于初始和重复干预的成功率相等,因此在临床过程允许的情况下,应进行重复干预。