Farg Hashim Mohamed, Elawdy Mohamed Mohamed, Soliman Karim Ali, Badawy Mohamed Ali, Elsorougy Ali, Abdelhamid Abdalla, Mohsen Tarek, El-Diasty Tarek
Department of Radiology, Urology and Nephrology Centre, Mansoura University, Mansoura, Egypt.
Department of Urology, Urology and Nephrology Centre, Mansoura University, Mansoura, Egypt.
Asian J Urol. 2022 Apr;9(2):103-108. doi: 10.1016/j.ajur.2021.07.003. Epub 2021 Jul 27.
The aim of this study was to evaluate the predictor of unsuccessful outcome of renal angioembolization (RAE). Knowing those predictors may help in avoiding unnecessary RAE procedures and their associated side effects, while helping to prepare for an alternate procedure and improving patient's overall satisfaction.
A retrospective analysis between January 2006 and December 2018 was performed, and the indications for RAE were classified into post-traumatic, iatrogenic, renal tumors, and spontaneous. Patients who underwent RAE prior to nephrectomy were eliminated. Computed tomography angiography was performed in patients with normal renal function and those who had no contrast allergy, otherwise magnetic resonance angiography was performed. For the purpose of statistical analysis, we stratified patients into two main categories based on the final outcome-successful or failed.
Of 180 patients, 32 with negative angiography were eliminated, leaving 148 patients; 136 (91%) had successful outcomes after one or more trials and 12 had unsuccessful outcomes. The mean age was 45±15 years, and 105 (71%) were male. Neither gender, side of the lesion, presence of hematuria, indication for RAE, nor the type of lesion affected the outcome. On the other hand, renal anatomy with presence of accessory artery was the only predictor to failed RAE (=0.001). Failed RAE trial was a predictor for nephrectomy as a secondary procedure (=0.03).
No pre-procedural predictors could anticipate the RAE outcome, and different indications can be scheduled to RAE, which is equally effective. The presence of accessory renal artery on diagnostic angiography is the only factor that may predict the failure of the procedure.
本研究旨在评估肾血管栓塞术(RAE)治疗失败的预测因素。了解这些预测因素有助于避免不必要的RAE手术及其相关副作用,同时有助于为替代手术做好准备并提高患者的总体满意度。
对2006年1月至2018年12月期间进行回顾性分析,将RAE的适应证分为创伤后、医源性、肾肿瘤和自发性。排除在肾切除术前行RAE的患者。对肾功能正常且无造影剂过敏的患者进行计算机断层血管造影,否则进行磁共振血管造影。为了进行统计分析,我们根据最终结果(成功或失败)将患者分为两大类。
180例患者中,32例血管造影阴性者被排除,剩余148例患者;136例(91%)经过一次或多次尝试后治疗成功,12例治疗失败。平均年龄为45±15岁,105例(71%)为男性。性别、病变侧别、血尿的存在、RAE的适应证以及病变类型均不影响治疗结果。另一方面,存在副动脉的肾脏解剖结构是RAE治疗失败的唯一预测因素(=0.001)。RAE治疗失败是作为二次手术进行肾切除术的预测因素(=0.03)。
术前没有预测因素能够预判RAE的治疗结果,不同的适应证均可安排RAE,其效果相同。诊断性血管造影中存在副肾动脉是唯一可能预测手术失败的因素。