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[膀胱小细胞神经内分泌癌:一例病例报告及文献复习]

[Small cell neuroendocrine carcinoma of the bladder: A case report and review of the literature].

作者信息

Chekrine T, De Bari B, Cassier P, Kulisa M, Chapet O, Mornex F

机构信息

Département de radiothérapie-oncologie, centre hospitalier Lyon-Sud, chemin du Grand-Revoyet, Pierre-Bénite, France.

出版信息

Cancer Radiother. 2011 Jun;15(3):250-3. doi: 10.1016/j.canrad.2010.11.013. Epub 2011 Mar 21.

Abstract

Neuroendocrine small cell carcinoma of the bladder is a rare and aggressive cancer with a very pejorative behavior. Neuroendocrine small cell carcinoma of bladder is a histological entity with special characteristics, rapidly aggressive and metastatic and with a poor prognosis. Because it is rare, there is no consensus to date. Its management should be multidisciplinary, involving surgery, chemotherapy and radiotherapy. We report the case of an 84-year-old patient with neuroendocrine small cell carcinoma of the bladder, treated by neoadjuvant chemotherapy followed by a combined chemoradiotherapy. A review of the literature on this topic is also presented.

摘要

膀胱神经内分泌小细胞癌是一种罕见且侵袭性强的癌症,具有非常恶劣的行为。膀胱神经内分泌小细胞癌是一种具有特殊特征的组织学实体,具有快速侵袭性和转移性,预后较差。由于其罕见性,迄今为止尚无共识。其治疗应是多学科的,包括手术、化疗和放疗。我们报告了一例84岁膀胱神经内分泌小细胞癌患者的病例,该患者接受了新辅助化疗,随后进行了放化疗联合治疗。本文还对该主题的文献进行了综述。

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