Hensten-Pettersen A, Jacobsen N
NIOM, Scandinavian Institute of Dental Materials, Haslum, Norway.
Int Dent J. 1990 Jun;40(3):159-66.
Many of the biomaterials and auxilliary products used in dentistry are chemically and biologically reactive and may be of concern in occupational safety programmes. Observations from 1936 to 1975 indicated that most occupational problems were related to skin contact with procaine, soaps, eugenol, iodine, formalin, phenol, and other disinfectants. Methyl methacrylate monomer was identified as an irritant and allergen in the later part of this period. Investigations from 1975 to 1985 indicated that disinfectants and detergents were still important causes of dermatoses, whereas reactions to procaine had been replaced by reactions to pantocaine. Furthermore, adverse reactions to methyl methacrylate monomer and to elastomeric impression materials had replaced the former iodine, tricresol and eugenol reactions. In recent studies the frequency of occupation-related dermatoses varied from 21 per cent to 43 per cent, depending on the prevailing material usage in the various specialties. Reactions to local anaesthetics seemed to have disappeared. Transient, irritative reactions of the eyes and airways have been observed, mostly associated with exposure to volatiles from resin-based materials, X-ray chemicals and cleansers. The occupational problems related to biomaterials in dentistry seem to have been fairly constant over the years, reflecting the type of materials in common use, and with dermatological disorders being a tenacious companion. Neuropathological conditions in dental technicians have been associated with prolonged exposure to vapours of methyl methacrylate monomer. The more recent extensive use of volatile resin-based materials, and the use of protective gloves seems to have created new problems that need to be investigated.
牙科中使用的许多生物材料和辅助产品具有化学和生物反应性,可能在职业安全计划中受到关注。1936年至1975年的观察表明,大多数职业问题与皮肤接触普鲁卡因、肥皂、丁香酚、碘、福尔马林、苯酚和其他消毒剂有关。甲基丙烯酸甲酯单体在这一时期后期被确定为一种刺激物和过敏原。1975年至1985年的调查表明,消毒剂和洗涤剂仍然是皮肤病的重要病因,而对普鲁卡因的反应已被对潘托卡因的反应所取代。此外,对甲基丙烯酸甲酯单体和弹性印模材料的不良反应已取代了以前对碘、三甲酚和丁香酚的反应。在最近的研究中,与职业相关的皮肤病发生率从21%到43%不等,这取决于各专业中主要使用的材料。对局部麻醉剂的反应似乎已经消失。已观察到眼睛和呼吸道的短暂刺激性反应,主要与接触树脂基材料、X射线化学药品和清洁剂的挥发物有关。多年来,牙科中与生物材料相关的职业问题似乎相当稳定,这反映了常用材料的类型,皮肤病一直与之相伴。牙科技术人员的神经病理状况与长期接触甲基丙烯酸甲酯单体的蒸汽有关。最近挥发性树脂基材料的广泛使用以及防护手套的使用似乎产生了一些需要研究的新问题。