老年人嗅觉障碍与抑郁症状和较差的生活质量评分有关。
Olfactory impairment in older adults is associated with depressive symptoms and poorer quality of life scores.
机构信息
Centre for Vision Research, Department of Ophthalmology and Westmead Millennium Institute, University of Sydney, Australia.
出版信息
Am J Geriatr Psychiatry. 2011 Sep;19(9):830-4. doi: 10.1097/JGP.0b013e318211c205.
OBJECTIVES
We assessed the association between impaired olfaction and depressive symptoms and poor quality of life.
METHODS
A total of 1,375 participants aged 60 years or older had their olfaction measured using the San Diego Odor Identification Test. Quality of life was assessed using the 36-Item Short-Form Survey (SF-36). Depressive symptoms were assessed by either the SF-36, which included the Mental Health Index, and/or the Center for Epidemiologic Studies Depression Scale (CES-D-10).
RESULTS
Among participants with olfactory impairment, 15.4% and 20.2% had depressive symptoms assessed by the Mental Health Index and CES-D-10, respectively. Among participants aged 70 years or older, olfactory impairment was associated with depressive symptoms (assessed by the CES-D-10), multivariate-adjusted odds ratio, OR: 1.66 (95% confidence interval, CI: 1.03-2.66). Subjects with olfactory impairment compared to those without, had lower SF-36 scores in six out of the eight indices.
CONCLUSIONS
Olfactory impairment was independently associated with depressive symptoms and poorer quality of life.
目的
我们评估了嗅觉障碍与抑郁症状和生活质量差之间的关系。
方法
共有 1375 名 60 岁或以上的参与者使用圣地亚哥嗅觉识别测试来测量他们的嗅觉。使用 36 项简短健康调查（SF-36）来评估生活质量。抑郁症状通过 SF-36 中的心理健康指数和/或流行病学研究中心抑郁量表（CES-D-10）来评估。
结果
在嗅觉障碍的参与者中，分别有 15.4%和 20.2%的参与者通过心理健康指数和 CES-D-10 评估出有抑郁症状。在 70 岁或以上的参与者中，嗅觉障碍与抑郁症状（通过 CES-D-10 评估）相关，多变量调整后的优势比（OR）为 1.66（95%置信区间（CI）：1.03-2.66）。与没有嗅觉障碍的人相比，有嗅觉障碍的人在八项指标中的六项指标中 SF-36 得分较低。
结论
嗅觉障碍与抑郁症状和较差的生活质量独立相关。
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