Walsh Thomas L, Homa Karen, Hanscom Brett, Lurie Jon, Sepulveda Maria Grau, Abdu William
The Spine Center, Department of Orthopedics at Dartmouth Hitchcock Medical Center, One Medical Center Drive, Lebanon, NH 03756, USA.
Spine J. 2006 May-Jun;6(3):316-20. doi: 10.1016/j.spinee.2005.11.004.
Depression is a common co-morbidity for patients with complaints of spinal pain, yet often goes undiagnosed in clinical practice. Depressed patients who are not identified do not receive a referral or recommendation for treatments that may help ease their total illness burden. Relative to the total outcomes of spine care this may increase costs, decrease overall functional outcomes, and limit patient satisfaction. Some spine care settings track functional outcomes using a general health status survey. Although a specific and reliable survey to detect depression could be employed, an additional survey would unnecessarily increase responder and analyst burdens if the general health status survey could be used instead.
To identify the Mental Component Summary (MCS) cutoff score from the Short Form 36-item Health Survey (SF-36) that best predicts a positive depression score as measured by the Center for Epidemiological Study-Depression Survey (CES-D).
An analysis of the diagnostic properties of the SF-36 MCS Scale as a predictor of depressive symptoms as measured by the CES-D.
The SF-36 is a general health survey that contains a MCS score that represents the psychological well-being and general health perception of the respondent. This composite score is norm-based (mean = 50, SD = 10) with lower scores representing poorer health. The CES-D has been well-studied in patients with chronic pain complaints and was used as the gold standard for determining the MCS cutoff score. A CES-D score of 19 or greater was considered positive for depressive symptoms.
All patients entering our facility routinely complete the SF-36. Between February 2002 and October 2002, all patients scoring 30 or less on the MCS (MCS < or = 30) also completed the CES-D. Patients who scored 2 standard deviations below the mean (MCS = 30 or less) were considered most at risk for depression. Patients scoring above 30 on their MCS (MCS > 30) were considered less likely to have depressive symptoms and were randomly chosen to complete the CES-D. There were 420 patients who completed both surveys of which there were 99 MCS < or = 30 patients and 321 MCS > 30 patients.
Receiver operating characteristic (ROC) curves were used to assess the sensitivity and specificity of the SF-36 as a screening tool for detecting depressive symptoms.
An MCS score of 35 has a sensitivity of 80% (76-83; 95% confidence interval), a specificity of 90% (87-93), an ROC area of 0.8517 (0.81-0.89), and correctly identified 87% of the sample.
The SF-36 provides the benefits of a general functional health status measure and additionally appears to provide a screening tool for depressive symptoms. A cutoff score of 35 or less on the MCS scale has a high degree of sensitivity and specificity and is able to identify depressive symptoms in patients with back pain, which can help identify patients who will benefit from mental health treatments.
抑郁症是脊柱疼痛患者常见的共病,但在临床实践中常常未被诊断出来。未被识别的抑郁症患者无法获得有助于减轻其整体疾病负担的转诊或治疗建议。相对于脊柱护理的总体结果,这可能会增加成本、降低整体功能结果并限制患者满意度。一些脊柱护理机构使用一般健康状况调查来跟踪功能结果。虽然可以采用一项专门且可靠的调查来检测抑郁症,但如果可以改用一般健康状况调查,额外的调查将不必要地增加应答者和分析人员的负担。
从简短36项健康调查(SF - 36)中确定精神成分总结(MCS)的临界值,该临界值能最佳预测由流行病学研究中心抑郁量表(CES - D)测量得出的阳性抑郁得分。
分析SF - 36 MCS量表作为CES - D测量的抑郁症状预测指标的诊断特性。
SF - 36是一项一般健康调查,包含一个MCS得分,该得分代表应答者的心理健康和总体健康感知。这个综合得分基于常模(均值 = 50,标准差 = 10),得分越低表示健康状况越差。CES - D在慢性疼痛患者中已得到充分研究,并被用作确定MCS临界值的金标准。CES - D得分19或更高被认为抑郁症状呈阳性。
所有进入我们机构的患者常规完成SF - 36调查。在2002年2月至2002年10月期间,所有MCS得分30分及以下(MCS≤30)的患者也完成了CES - D调查。得分比均值低2个标准差(MCS = 30或更低)的患者被认为患抑郁症风险最高。MCS得分高于30分(MCS > 30)的患者被认为抑郁症状可能性较小,并被随机挑选完成CES - D调查。共有420名患者完成了两项调查,其中99名患者MCS≤30,321名患者MCS > 30。
使用受试者操作特征(ROC)曲线评估SF - 36作为检测抑郁症状筛查工具的敏感性和特异性。
MCS得分35时,敏感性为80%(76 - 83;95%置信区间),特异性为90%(87 - 93),ROC曲线下面积为0.8517(0.81 - 0.89),正确识别了87%的样本。
SF - 36既提供了一般功能健康状况测量的益处,此外似乎还提供了一种抑郁症状筛查工具。MCS量表得分35分及以下具有高度的敏感性和特异性,能够识别背痛患者中的抑郁症状,这有助于识别将从心理健康治疗中获益的患者。