碱催化的稠杂环体系螺环化合物的多组分合成。
Base catalyzed multicomponent synthesis of spiroheterocycles with fused heterosystems.
机构信息
Department of Chemistry, University of Rajasthan, Jaipur 302055, India.
出版信息
Mol Divers. 2011 Aug;15(3):781-9. doi: 10.1007/s11030-011-9309-2. Epub 2011 Mar 20.
PMID:21424596
Abstract
Structurally diverse spiroheterocycles incorporating medicinally privileged heterosystems have been synthesized by a simple and convenient synthesis involving triethylamine catalyzed multicomponent domino reaction of 2-aminobenzothiazoles with isatin and cyclic 1,3-diketones.
摘要
通过简单方便的三乙胺催化 2-氨基苯并噻唑与色酮和环状 1,3-二酮的多组分级联反应，合成了具有药用优势杂环的结构多样的螺杂环化合物。
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