Mühlenstädt E, Mokosch A, Homey B, Reifenberger J
Hautklinik des Universitätsklinikums Düsseldorf, Heinrich-Heine-Universität Düsseldorf, Moorenstr. 5, 40225, Düsseldorf Deutschland.
Hautarzt. 2011 Apr;62(4):252-5. doi: 10.1007/s00105-011-2149-2.
Erythema elevatum et diutinum (EED) is a rare, chronic, cutaneous, leukocytoclastic vasculitis. It is characterized by symmetric, plaques, papules and nodules occurring preferentially on the extensor aspects of the arms. An association with chronic infections, neoplasms, especially myeloproliferative diseases and paraproteinemia, as well as autoimmune disorders (rheumatoid arthritis, Crohn disease) has been described. An 83-year-old woman with EED presented with symmetric, skin colored, firm nodules on the extensor surfaces of her fingers for two years. This case report summarizes the central clinical aspects and differential diagnosis of EED as well as its therapeutic options.
持久性隆起性红斑(EED)是一种罕见的慢性皮肤白细胞破碎性血管炎。其特征为对称性斑块、丘疹和结节,好发于手臂伸侧。已报道其与慢性感染、肿瘤,尤其是骨髓增殖性疾病和副蛋白血症以及自身免疫性疾病(类风湿性关节炎、克罗恩病)有关。一名患有EED的83岁女性,其手指伸侧出现对称性、肤色、坚实的结节,病程已两年。本病例报告总结了EED的主要临床特征、鉴别诊断及其治疗选择。