Gharedaghi Mohammad, Mohammadzadeh Ashraf, Zandi Behrooz
Department of Orthopedic Surgery, Neonatal Research Center, School of Medicine, Mashhad, University of Medical Science, Iran.
Acta Med Iran. 2011;49(1):25-7.
Developmental dysplasia of the hip (DDH) is one of the most widely discussed abnormalities in neonates. The advantages of sonographic examination are well known, but its main disadvantage is that it might lead to over diagnosis, which might cause over treatment. Variations in the incidence of developmental dysplasia of the hip are well known. During six months study since September 2006 all 1300 neonates (2600 hips) were born in our hospital examined clinically and sonographically (587 hips) in the first 48 hours of life. Sonography was performed according to Graf's method, which considers mild hip sonographic abnormalities as type II a. Type IIb Graf were considered pathologic. Sonography screening of 587 hips detected 36 instances of deviation from normal indicating a sonographic DDH incidence of 12.5%. However, only 8 neonates remained abnormal and required treatment, indicating a true DDH incidence of 6 per 1000 live birth. Risk of diagnosis clinically and sonographicaly were 2.5 and 4.5 percent respectively and was significant (P<0.00001, x(2)=1170). In order to avoid over diagnosis in first days examination, repeated clinical and sonographic examination is required.
发育性髋关节发育不良(DDH)是新生儿中讨论最为广泛的异常情况之一。超声检查的优点众所周知,但其主要缺点是可能导致过度诊断,进而可能造成过度治疗。髋关节发育不良的发病率存在差异,这是广为人知的。自2006年9月起的6个月研究期间,我院出生的所有1300例新生儿(2600个髋关节)在出生后的头48小时内接受了临床检查和超声检查(587个髋关节)。超声检查按照格拉夫(Graf)方法进行,该方法将轻度髋关节超声异常视为II a型。格拉夫II b型被视为病理性的。对587个髋关节进行的超声筛查发现36例偏离正常情况,表明超声检查诊断的DDH发病率为12.5%。然而,只有8例新生儿仍存在异常并需要治疗,表明实际DDH发病率为每1000例活产中有6例。临床诊断风险和超声诊断风险分别为2.5%和4.5%,且具有显著性(P<0.00001,x(2)=1170)。为避免在首日检查中出现过度诊断,需要进行重复的临床和超声检查。