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尼日利亚拉各斯低出生体重婴儿的产妇危险因素。

Maternal risk factors for low birth weight babies in Lagos, Nigeria.

机构信息

Department of Obstetrics and Gynaecology, University Teaching Hospital, Ado Ekiti, Ekiti, Nigeria.

出版信息

Arch Gynecol Obstet. 2012 Jan;285(1):1-6. doi: 10.1007/s00404-011-1885-y. Epub 2011 Mar 24.

DOI:10.1007/s00404-011-1885-y
PMID:21431841
Abstract

PURPOSE

This case control study, which was prospective in design, was carried out in Lagos, Nigeria at the Lagos University Teaching Hospital. The aim was to determine the prevalence of and identify the risk factors for low birth weight deliveries.

METHODS

Using a pre-structured questionnaire, information about the sociodemographic, past obstetric history and the index pregnancy were obtained.

RESULTS

A total of 460 questionnaires were analyzed [155 women with LBW deliveries (cases) and 305 women with babies that weighed ≥2500 g who served as controls]. 1,097 births occurred during the study period, giving an incidence of 14.1%. Maternal age and parity were not significant risk factors. Not being booked in a tertiary institution [Odds ratio (OR) 0.39, 95% Confidence Interval (CI) 0.20-0.73, p < 0.05], previous history of LBW birth(s) (OR 2.42, 95% CI 1.02-5.81, p < 0.05), hypertensive disorder in index pregnancy (χ (2) = 50.18, p < 0.001), preterm rupture of membranes (OR 25.06, 95% CI 5.59-156.49, p < 0.001) and bleeding in pregnancy (OR 2.44, 95% CI 1.61-7.34, p < 0.001) were significantly associated with increased risk of LBW babies. However HIV infection, sickle cell disease, maternal height, occupation and level of education were not significant (p > 0.05).

CONCLUSIONS

Preconceptual care, efficient antenatal care and effective treatment of pelvic infections (which may predispose to preterm births) could reduce the incidence of low birth weight deliveries in Nigeria.

摘要

目的

本病例对照研究为前瞻性设计,在尼日利亚拉各斯的拉各斯大学教学医院进行。目的是确定低出生体重儿分娩的发生率,并确定其危险因素。

方法

使用预先设计的问卷,获取社会人口统计学、既往产科史和本次妊娠的信息。

结果

共分析了 460 份问卷[155 名低出生体重儿分娩的妇女(病例)和 305 名体重≥2500g 的婴儿的妇女作为对照]。在研究期间共发生了 1097 例分娩,发生率为 14.1%。母亲年龄和产次不是显著的危险因素。未在三级机构建档[优势比(OR)0.39,95%置信区间(CI)0.20-0.73,p<0.05]、既往有低出生体重儿分娩史(OR 2.42,95%CI 1.02-5.81,p<0.05)、本次妊娠存在高血压疾病(χ2=50.18,p<0.001)、胎膜早破(OR 25.06,95%CI 5.59-156.49,p<0.001)和妊娠出血(OR 2.44,95%CI 1.61-7.34,p<0.001)与低出生体重儿的风险增加显著相关。然而,艾滋病毒感染、镰状细胞病、母亲身高、职业和教育程度均无显著相关性(p>0.05)。

结论

在尼日利亚,孕前保健、高效的产前保健和有效的骨盆感染治疗(可能导致早产)可降低低出生体重儿的发生率。

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