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零食摄入对敏感唾液应激标志物皮质醇和嗜铬粒蛋白 A 的影响。

Effect of snack eating on sensitive salivary stress markers cortisol and chromogranin A.

机构信息

Department of Social and Environmental Medicine, Osaka University Graduate School of Medicine, 2-2 Yamada-Oka, 565-0871, Suita, Osaka, Japan.

出版信息

Environ Health Prev Med. 2004 Jan;9(1):27-9. doi: 10.1265/ehpm.9.27.

Abstract

OBJECTIVES

To investigate the effect of snack eating on salivary cortisol and chromogranin A (CgA).

METHODS

From 14∶00 to 18∶00, starting two hours after consumption of a midday meal, saliva samples were collected every 30 minutes from 15 healthy males, 7 of whom (snack group) ate a snack immediately after the sampling at 15∶00. Salivary cortisol and CgA levels were determined by ELISA. Samples were controlled according to salivary flow rates.

RESULTS

For the snack group, after snack consumption, salivary cortisol increased to exceed significance (p<0.05) at 15∶30 and rose even higher at 16∶00. In the control group, there was no such change. There was no significant change in salivary CgA in either the snack group or the control groups during the sampling period.

CONCLUSIONS

These findings suggest that no food should be consumed for at least 90 mins before saliva sampling for cortisol determination and that salivary CgA is probably not affected by snack eating.

摘要

目的

研究吃零食对唾液皮质醇和嗜铬粒蛋白 A(CgA)的影响。

方法

15 名健康男性从 14:00 到 18:00,在午饭后两小时开始,每 30 分钟采集一次唾液样本,其中 7 人(零食组)在 15:00 采样后立即吃零食。通过 ELISA 法测定唾液皮质醇和 CgA 水平。样本根据唾液流速进行控制。

结果

对于零食组,在吃零食后,唾液皮质醇在 15:30 分升高至有统计学意义(p<0.05),在 16:00 分进一步升高。在对照组中,没有发生这种变化。在零食组和对照组中,在采样期间,唾液 CgA 均无明显变化。

结论

这些发现表明,在进行皮质醇测定的唾液采样前,至少 90 分钟内不应进食任何食物,而且零食摄入可能不会影响唾液 CgA。

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