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脑组织中的腺苷酸环化酶和磷酸二酯酶：大脑皮层切片孵育期间的不同稳定性

Adenylate cyclase and phosphodiesterase from brain tissue: different stabilities during incubation of cerebral cortical slices.

作者信息

Schultz J, Kleefeld G, du Moulin A

出版信息

Experientia. 1978 Nov 15;34(11):1432-3. doi: 10.1007/BF01932331.

DOI:10.1007/BF01932331
PMID:214325
Abstract

Adenylate cyclase and phosphodiesterase were prepared from brain slices from guinea-pig. The specific activity of adenylate cyclase declined rapidly with increasing incubation time of tissue slices, while phosphodiesterase activity was almost uneffected by the incubation of brain slices.

摘要

腺苷酸环化酶和磷酸二酯酶是从豚鼠脑切片中制备的。腺苷酸环化酶的比活性随着组织切片孵育时间的增加而迅速下降，而磷酸二酯酶的活性几乎不受脑切片孵育的影响。

相似文献

1
Adenylate cyclase and phosphodiesterase from brain tissue: different stabilities during incubation of cerebral cortical slices.脑组织中的腺苷酸环化酶和磷酸二酯酶：大脑皮层切片孵育期间的不同稳定性
Experientia. 1978 Nov 15;34(11):1432-3. doi: 10.1007/BF01932331.
2
Adenylate cyclase-phosphodiesterase system in rat olfactory bulb and cerebral cortex during the postnatal period. Effects of growth restriction.出生后大鼠嗅球和大脑皮层中的腺苷酸环化酶-磷酸二酯酶系统。生长受限的影响。
Brain Res. 1980 Jul 14;193(2):598-603. doi: 10.1016/0006-8993(80)90197-3.
3
Subcellular distribution of adenylate cyclase and cyclic adenosine monophosphate phosphodiesterase in rat and guinea-pig deferens.
Neuroscience. 1980;5(8):1461-5. doi: 10.1016/0306-4522(80)90007-x.
4
Activation of adenyl cyclase and adenosine 3',5'-monophosphate phosphodiesterase in rat brain synaptosomes.大鼠脑突触体中腺苷酸环化酶和3',5'-环磷酸腺苷磷酸二酯酶的激活
Chem Pharm Bull (Tokyo). 1976 May;24(5):1064-7. doi: 10.1248/cpb.24.1064.
5
Interactions of antiepileptic drugs on adenylate cyclase and phosphodiesterases in rat and mouse cerebrum.抗癫痫药物对大鼠和小鼠大脑中腺苷酸环化酶和磷酸二酯酶的相互作用。
Exp Neurol. 1979 Feb;63(2):322-35. doi: 10.1016/0014-4886(79)90128-6.
6
Excitation-secretion coupling in exocrine glands. Properties of cyclic AMP phosphodiesterase and adenylate cyclase from the submaxillary gland and pancreas.外分泌腺中的兴奋-分泌偶联。下颌下腺和胰腺中环磷酸腺苷磷酸二酯酶和腺苷酸环化酶的特性。
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Beta 1-adrenergic selectivity of the new cardiotonic agent denopamine in its stimulating effects on adenylate cyclase.新型强心剂多巴胺对腺苷酸环化酶刺激作用的β1-肾上腺素能选择性
Biochem Pharmacol. 1987 Jun 15;36(12):1947-54. doi: 10.1016/0006-2952(87)90493-x.
8
Adenylate cyclase and cyclic AMP phosphodiesterase activity during the mitotic cycle of Physarum polycephalum.
Biochem Biophys Res Commun. 1978 Nov 29;85(2):579-84. doi: 10.1016/0006-291x(78)91202-0.
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The in vitro effect of ethanol on the histamine-sensitive adenylate cyclase system.乙醇对组胺敏感腺苷酸环化酶系统的体外效应。
Agents Actions. 1981 Apr;11(1-2):158-60. doi: 10.1007/BF01991488.
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Interactions of gangliosides with adenylate cyclase and cyclic AMP phosphodiesterase in rat brain homogenates and synaptosomes [proceedings].神经节苷脂与大鼠脑匀浆和突触体中腺苷酸环化酶及环磷酸腺苷磷酸二酯酶的相互作用[会议论文集]
Biochem Soc Trans. 1980 Feb;8(1):128-9. doi: 10.1042/bst0080128.

本文引用的文献

1
Adenyl cyclase. IV. The effects of neurohormones on the formation of adenosine 3',5'-phosphate by preparations from brain and other tissues.腺苷酸环化酶。IV. 神经激素对脑及其他组织提取物中3',5'-磷酸腺苷形成的影响。
J Biol Chem. 1962 Apr;237:1239-43.
2
Cyclic adenosine 3',5'-monophosphate in guinea pig cerebral cortical slices. I. Formation of cyclic adenosine 3',5'-monophosphate from endogenous adenosine triphosphate and from radioactive adenosine triphosphate formed during a prior incubation with radioactive adenine.豚鼠大脑皮质切片中的环磷酸腺苷3',5'-单磷酸。I. 由内源性三磷酸腺苷以及在先前与放射性腺嘌呤孵育期间形成的放射性三磷酸腺苷形成环磷酸腺苷3',5'-单磷酸。
J Biol Chem. 1973 Feb 10;248(3):843-52.
3
Assay of phosphodiesterase with radioactively labeled cyclic 3',5'-AMP as substrate.
以放射性标记的环3',5'-AMP为底物的磷酸二酯酶测定法。
Naunyn Schmiedebergs Arch Pharmakol. 1971;268(3):272-99. doi: 10.1007/BF00997262.
4
Multiple cyclic nucleotide phosphodiesterase activities from rat brain.大鼠脑中的多种环核苷酸磷酸二酯酶活性
Biochemistry. 1971 Jan 19;10(2):311-6.
5
A protein binding assay for adenosine 3':5'-cyclic monophosphate.一种用于检测3':5'-环磷酸腺苷的蛋白质结合测定法。
Proc Natl Acad Sci U S A. 1970 Sep;67(1):305-12. doi: 10.1073/pnas.67.1.305.
6
Catecholamine-sensitive adenylate cyclases in nervous tissues.
J Neurochem. 1977 Jul;29(1):5-12. doi: 10.1111/j.1471-4159.1977.tb03918.x.