Ebner Natalie C, Gluth Sebastian, Johnson Matthew R, Raye Carol L, Mitchell Karen J, Johnson Marcia K
Department of Psychology, Yale University, New Haven, CT, USA.
Neurocase. 2011 Jun;17(3):260-9. doi: 10.1080/13554794.2010.536953.
This functional magnetic resonance imaging study examined medial prefrontal cortex (mPFC) activity as young and older participants rated an unknown young and older person, and themselves, on personality characteristics. For both young and older participants, there was greater activation in ventral mPFC (anterior cingulate) when they made judgments about own-age than other-age individuals. Additionally, across target age and participant age, there was greater activity in a more anterior region of ventral mPFC (largely medial frontal gyrus, anterior cingulate) when participants rated others than when they rated themselves. We discuss potential interpretations of these findings in the context of previous results suggesting functional specificity of subregions of ventral mPFC.
这项功能磁共振成像研究考察了年轻和年长参与者在根据个性特征对一名陌生的年轻人和年长者以及对自己进行评分时内侧前额叶皮质（mPFC）的活动。对于年轻和年长参与者而言，当他们对同龄人而非其他年龄段的个体进行判断时，腹侧mPFC（前扣带回）的激活程度更高。此外，在不同的目标年龄和参与者年龄组中，当参与者对他人进行评分时，腹侧mPFC更靠前的区域（主要是内侧额回、前扣带回）的活动比他们对自己评分时更活跃。我们结合之前表明腹侧mPFC各亚区功能特异性的研究结果，讨论了这些发现的潜在解释。
