1,2-取代催产素类似物与子宫受体的亲和力：Free-Wilson法和Hansch分析法
Affinity of 1,2-substituted oxytocin analogues to the uterus receptor: Free-Wilson and Hansch analysis.
作者信息
Pliska V
出版信息
Experientia. 1978 Sep 15;34(9):1190-2. doi: 10.1007/BF01922951.
PMID:214332
Abstract
The analysis of pA2 values for 1,2-substituted oxytocin analogues suggests a significant resonance effect of p-substituted groups in 2-tyrosine when the hormone binds to its uterus receptor, whereas the N-terminal amino group exerts less clearly characterized effects (participation of its lipophilicity and molecular volume can be assumed.
摘要
对1,2-取代的催产素类似物的pA2值分析表明，当该激素与其子宫受体结合时，2-酪氨酸中对位取代基团存在显著的共振效应，而N-末端氨基产生的效应特征不太明显（可以假定其亲脂性和分子体积起了作用）。
Zotero 插件