New York College of Osteopathic Medicine, New York Institute of Technology, Old Westbury, NY, USA.
Am J Ther. 2013 May-Jun;20(3):307-10. doi: 10.1097/MJT.0b013e3181f6c131.
Although it is common to find metastases of transitional cell carcinoma of the bladder to the lymph nodes, lung, bone, and liver, cardiac metastases have only been rarely reported. We report a case of symptomatic metastasis of transitional cell cancer to the right ventricle. A 59-year-old man with a history of transitional cell bladder cancer status post cystectomy and chemotherapy, with neobladder placement, presented with hematuria, shortness of breath, murmur, and evidence of right-sided heart failure. On imaging workup, including transthoracic echocardiography and cardiac computed tomography, we found a large right ventricular mass. A review of the literature showed that there are only 9 cases of cardiac metastasis from transitional cell cancer reported; however, our case is unique because it is the only reported case of symptomatic improvement due to effective treatment with chemotherapy.
尽管膀胱癌的淋巴结、肺、骨和肝转移较为常见,但心脏转移却很少见。我们报告了一例有症状的膀胱癌转移至右心室的病例。一名 59 岁男性,膀胱癌行膀胱切除术和化疗后,行回肠新膀胱术,现因血尿、呼吸困难、杂音和右侧心力衰竭的证据就诊。影像学检查包括经胸超声心动图和心脏计算机断层扫描,发现右心室有一个大肿块。文献复习显示,仅有 9 例膀胱癌心脏转移的病例报告;然而,我们的病例是独特的,因为它是唯一一例因化疗有效而症状改善的报道。