Department of Urology, Korea Cancer Center Hospital, Seoul, Republic of Korea.
J Endourol. 2011 Apr;25(4):597-602. doi: 10.1089/end.2010.0229. Epub 2011 Mar 25.
To directly compare the outcome of laparoscopic radical prostatectomy (LRP) with robot-assisted laparoscopic prostatectomy (RALP) performed by a single laparoscopic surgeon with intermediate experience-one who is between a novice and an expert.
Consecutive 106 patients with prostate cancer who were treated with radical prostatectomy (62 with LRP and 44 with RALP) were included. The preoperative characteristics, the perioperative surgical outcomes, and the functional outcomes were compared between the two groups.
The mean operative time was longer in the RALP group (371 min vs 308 min, P = 0.00), conceivably because of more nerve-sparing procedures (84% vs 57%). The other perioperative parameters, including the surgical margin, were comparable, except for two major complications (rectourethral fistula and ureteral injury) in the LRP group. The RALP group recovered continence faster than those in the LRP, but the eventual continence rate at 12 months was similar (95% for LRP vs 94.4% for RALP, P = 1.00). The potency rate ≥ 6 months postsurgery was 47.6% in the LRP group and 54.5% in the RALP group (P = 0.65).
RALP was beneficial for the earlier recovery of continence, although LRP and RALP had comparable safety and efficacy as minimally invasive surgery for prostate cancer when performed by a laparoscopic surgeon with intermediate experience. Long-term follow-up data are needed for further evaluation of oncologic and functional outcomes for both techniques.
直接比较由一位具有中级经验的腹腔镜外科医生(即处于新手和专家之间的医生)进行的腹腔镜根治性前列腺切除术(LRP)与机器人辅助腹腔镜前列腺切除术(RALP)的结果。
连续纳入 106 例接受根治性前列腺切除术(62 例接受 LRP,44 例接受 RALP)的前列腺癌患者。比较两组患者的术前特征、围手术期手术结果和功能结果。
RALP 组的平均手术时间更长(371 分钟 vs 308 分钟,P=0.00),可能是因为该组进行了更多的神经保护手术(84% vs 57%)。除了 LRP 组的两个主要并发症(直肠尿道瘘和输尿管损伤)外,其他围手术期参数(包括切缘)均相似。RALP 组比 LRP 组更快恢复尿控,但 12 个月时的最终尿控率相似(LRP 为 95%,RALP 为 94.4%,P=1.00)。LRP 组术后 6 个月时的勃起功能≥6 个月的比例为 47.6%,RALP 组为 54.5%(P=0.65)。
RALP 有利于更快恢复尿控,尽管由具有中级经验的腹腔镜外科医生进行时,LRP 和 RALP 作为前列腺癌的微创手术具有相似的安全性和疗效。需要进行长期随访数据以进一步评估这两种技术的肿瘤学和功能结果。