Department of Melanoma, Sarcoma, and Head and Neck Disease, Istituto Nazionale Tumori Fondazione Pascale, Naples, Italy.
J Transl Med. 2011 Mar 26;9:32. doi: 10.1186/1479-5876-9-32.
Progress in understanding the molecular basis of melanoma has made possible the identification of molecular targets with important implications in clinical practice. In fact, new therapeutic approaches are emerging from basic science and it will be important to implement their rapid translation into clinical practice by active clinical investigation. The first meeting of Melanoma Research: a bridge Naples-USA, organized by Paolo A. Ascierto (INT, Naples, Italy) and Francesco Marincola (NIH, Bethesda, USA) took place in Naples, on 6-7 December 2010. This international congress gathered more than 30 international and Italian faculty members and was focused on recent advances in melanoma molecular biology, immunology and therapy, and created an interactive discussion across Institutions belonging to Government, Academy and Pharmaceutical Industry, in order to stimulate new approaches in basic, translational and clinical research. Four topics of discussion were identified: New pathways in Melanoma, Biomarkers, Clinical Trials and New Molecules and Strategies.
理解黑色素瘤分子基础方面的进展使得能够鉴定在临床实践中有重要意义的分子靶标。事实上,新的治疗方法正从基础科学中涌现出来,通过积极的临床研究将它们迅速转化为临床实践将非常重要。由 Paolo A. Ascierto(INT,意大利那不勒斯)和 Francesco Marincola(NIH,美国贝塞斯达)组织的第一次黑色素瘤研究:那不勒斯-美国桥梁会议于 2010 年 12 月 6 日至 7 日在那不勒斯举行。这次国际会议聚集了 30 多名国际和意大利教员,重点讨论了黑色素瘤分子生物学、免疫学和治疗方面的最新进展,并在政府、学术机构和制药行业所属的机构之间进行了互动讨论,以激发基础、转化和临床研究方面的新方法。确定了四个讨论主题:黑色素瘤的新途径、生物标志物、临床试验和新分子和策略。