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危重症患者的生物标志物:C 反应蛋白。

Biomarkers in the critically ill patient: C-reactive protein.

机构信息

Department of Intensive Care, Erasme Hospital, Université Libre de Bruxelles, 808, route de Lennik, 1070, Brussels, Belgium.

出版信息

Crit Care Clin. 2011 Apr;27(2):241-51. doi: 10.1016/j.ccc.2010.12.010.

DOI:10.1016/j.ccc.2010.12.010
PMID:21440199
Abstract

Levels of C-reactive protein (CRP), an acute phase protein, are elevated in many inflammatory conditions and are used to detect and follow disease in many fields of medicine, including rheumatology, gastroenterology, and cardiology. CRP concentrations are also used in critically ill patients, notably because they are increased during the inflammatory response to infection, that is, sepsis. However, CRP is not specific for sepsis, and serum CRP concentrations need to be interpreted in the context of a full clinical examination and the presence of other signs and symptoms of sepsis.

摘要

C-反应蛋白(CRP)是一种急性期蛋白,在许多炎症性疾病中水平升高,被用于检测和跟踪许多医学领域的疾病,包括风湿病学、胃肠病学和心脏病学。CRP 浓度也用于重症患者,特别是因为在感染引起的炎症反应期间增加,即脓毒症。然而,CRP 并非脓毒症特异性,血清 CRP 浓度需要结合全面的临床检查以及其他脓毒症的体征和症状进行解释。

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