Wallrabe D
Zentralinstitut für Herz-Kreislauf-Forschung Akademie der Wissenschaften der DDR Berlin-Buch.
Z Gesamte Inn Med. 1990 May 15;45(10):277-80.
In patients with arterial hypertension with and without LVH and in hypertrophic non-obstructive cardiomyopathy diastolic parameters were analyzed with M-mode and Doppler-Echocardiography. In hypertrophied hearts we could demonstrate, that Doppler estimated transmitral flow during rapid filling phase was significantly reduced. The lower early diastolic flow is compensated by an augmentation of atrial systole (higher A/R quotient). Diastolic filling anomalies are the consequence of impaired ventricular relaxation due to myocardial hypertrophy as could been proven by the M-mode derived isovolumetric relaxation time and retraction constant Te. Doppler echo is a very good tool for characterization of diastolic function not only in hypertrophied hearts, but also in coronary artery disease. Moreover it is possible to assess the efficiency of coronary artery bypass grafting or pharmacological interventions.
在伴有和不伴有左心室肥厚的动脉高血压患者以及肥厚型非梗阻性心肌病患者中，采用M型和多普勒超声心动图分析舒张参数。在肥厚型心脏中，我们可以证明，快速充盈期多普勒估计的二尖瓣血流显著减少。舒张早期血流降低通过心房收缩增强（更高的A/R比值）得到代偿。舒张期充盈异常是心肌肥厚导致心室舒张受损的结果，这已通过M型推导的等容舒张时间和回缩常数Te得到证实。多普勒超声不仅是表征肥厚型心脏舒张功能的良好工具，也是表征冠状动脉疾病舒张功能的良好工具。此外，还可以评估冠状动脉搭桥术或药物干预的效果。
