University of California San Diego, La Jolla, CA 92093-0507, USA.
Drug Alcohol Depend. 2011 Sep 1;117(2-3):219-25. doi: 10.1016/j.drugalcdep.2011.02.007. Epub 2011 Mar 26.
Agua celeste, or "heavenly water", is the street name for a sky-blue colored solvent reportedly inhaled or ingested to produce an intoxicating effect. Study aims were to (1) describe prevalence of agua celestse (AC) use, and (2) identify correlates of lifetime and recent use of AC use among female sex workers who also inject drugs (FSW-IDUs) in northern Mexico.
Between 2008 and 2010, baseline data from FSW-IDUs≥18 years old living in Tijuana or Ciudad Juarez participating in a longitudinal behavioral intervention were analyzed using logistic regression.
Among 623 FSW-IDUs (307 from Tijuana and 316 from Ciudad Juarez (CJ)), 166 (26%) reported ever using AC, all of whom lived in CJ. Among the CJ sample, lifetime prevalence of AC use was 53%, median age of first use was 16 years (IQR: 14-23), and 10% reported it as their first abused substance. Ever using AC was independently associated with ever being physically abused and younger age, and was marginally associated with initiating injection drug use and regular sex work at age eighteen or younger. Among those ever using AC, 70/166 (42.2%) reported using it within the last 6 months, which was independently associated with using drugs with clients before or during sex, being on the street more than 8h per day, and younger age.
We observed considerable geographic variation in the use of AC in northern Mexico. Future studies exploring factors influencing use, its precise formulation(s), and its potential health effects are needed to guide prevention and treatment.
“天之水”，或“蓝水”，是一种据称可吸入或摄入后产生致幻效果的天蓝色溶剂的街头名称。研究目的是：(1)描述“天之水”的使用情况，(2)确定在墨西哥北部注射吸毒的女性性工作者（FSW-IDUs）中，终生和近期使用“天之水”的相关因素。
在 2008 年至 2010 年间，对居住在提华纳或华雷斯城并参与纵向行为干预的年龄在 18 岁及以上的 FSW-IDUs 进行了分析，采用逻辑回归。
在 623 名 FSW-IDUs（307 名来自提华纳，316 名来自华雷斯城（CJ））中，166 名（26%）报告曾使用过“天之水”，他们均居住在 CJ。在 CJ 样本中，“天之水”的终生使用率为 53%，首次使用的中位年龄为 16 岁（IQR：14-23），10%的人将其作为首次滥用的物质。曾使用过“天之水”与曾遭受身体虐待和年龄较小独立相关，与 18 岁及以下开始使用注射毒品和定期从事性工作相关，呈边缘性相关。在曾使用过“天之水”的人群中，70/166（42.2%）报告在过去 6 个月内使用过，与与客户在发生性行为前后使用毒品、每天在街上的时间超过 8 小时以及年龄较小独立相关。
我们观察到墨西哥北部“天之水”的使用存在相当大的地域差异。需要进一步研究以探索影响其使用的因素、其确切的配方及其潜在的健康影响，以为预防和治疗提供指导。
