Future viral vectors for the delivery of asymptomatic herpes epitope-based immunotherapeutic vaccines.
作者信息
Chentoufi Aziz Alami, BenMohamed Lbachir
机构信息
Laboratory of Cellular & Molecular Immunology, The Gavin Herbert Eye Institute, University of California, Irvine, College of Medicine, Irvine, CA 92697-4375, USA.
出版信息
Future Virol. 2010 Sep 1;5(5):525-528. doi: 10.2217/fvl.10.44.
Abstract
摘要
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本文引用的文献
1
Viruses as vaccine vectors for infectious diseases and cancer.病毒作为传染性疾病和癌症的疫苗载体。
Nat Rev Microbiol. 2010 Jan;8(1):62-73. doi: 10.1038/nrmicro2240.
2
Protection from herpes simplex virus (HSV)-2 infection with replication-defective HSV-2 or glycoprotein D2 vaccines in HSV-1-seropositive and HSV-1-seronegative guinea pigs.在单纯疱疹病毒1型（HSV-1）血清阳性和血清阴性豚鼠中，用复制缺陷型单纯疱疹病毒2型（HSV-2）或糖蛋白D2疫苗预防HSV-2感染
J Infect Dis. 2009 Oct 1;200(7):1088-95. doi: 10.1086/605645.
3
Progress and prospects: biological properties and technological advances of herpes simplex virus type 1-based amplicon vectors.进展与展望：单纯疱疹病毒 1 型载体的生物学特性和技术进展。
Gene Ther. 2009 Jun;16(6):709-15. doi: 10.1038/gt.2009.42. Epub 2009 Apr 16.
4
Herpes simplex virus type 1 thymidine kinase sequence fused to the lacz gene increases levels of {beta}-galactosidase activity per genome of high-capacity but not first-generation adenoviral vectors in vitro and in vivo.与lacz基因融合的单纯疱疹病毒1型胸苷激酶序列可提高高容量腺病毒载体而非第一代腺病毒载体在体外和体内每个基因组的β-半乳糖苷酶活性水平。
J Virol. 2009 Feb;83(4):2004-10. doi: 10.1128/JVI.01298-08. Epub 2008 Dec 10.
5
Phase Ib trial of mutant herpes simplex virus G207 inoculated pre-and post-tumor resection for recurrent GBM.复发性胶质母细胞瘤患者在肿瘤切除前后接种突变型单纯疱疹病毒G207的Ib期试验。
Mol Ther. 2009 Jan;17(1):199-207. doi: 10.1038/mt.2008.228. Epub 2008 Oct 28.
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Herpes vector-mediated gene transfer in the treatment of chronic pain.疱疹病毒载体介导的基因转移在慢性疼痛治疗中的应用
Mol Ther. 2009 Jan;17(1):13-8. doi: 10.1038/mt.2008.213. Epub 2008 Oct 7.
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Ability of herpes simplex virus vectors to boost immune responses to DNA vectors and to protect against challenge by simian immunodeficiency virus.单纯疱疹病毒载体增强对DNA载体免疫反应及抵御猿猴免疫缺陷病毒攻击的能力。
Virology. 2007 Jan 20;357(2):199-214. doi: 10.1016/j.virol.2006.08.007. Epub 2006 Sep 7.
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HSV-1-mediated IL-1 receptor antagonist gene therapy ameliorates MOG(35-55)-induced experimental autoimmune encephalomyelitis in C57BL/6 mice.单纯疱疹病毒1型介导的白细胞介素-1受体拮抗剂基因治疗可改善C57BL/6小鼠中髓鞘少突胶质细胞糖蛋白（35-55）诱导的实验性自身免疫性脑脊髓炎。
Gene Ther. 2007 Jan;14(1):93-8. doi: 10.1038/sj.gt.3302805. Epub 2006 Aug 24.
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In vitro expansion of polyclonal T-cell subsets for adoptive immunotherapy by recombinant modified vaccinia Ankara.通过重组修饰安卡拉痘苗病毒进行多克隆T细胞亚群的体外扩增用于过继性免疫治疗
Exp Hematol. 2006 Apr;34(4):497-507. doi: 10.1016/j.exphem.2005.12.018.
10
Clinical trials of gene therapy, virotherapy, and immunotherapy for malignant gliomas.恶性胶质瘤的基因治疗、病毒治疗和免疫治疗的临床试验。
Cancer Gene Ther. 2006 Jun;13(6):539-54. doi: 10.1038/sj.cgt.7700930.
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