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[胚胎干细胞中通过间隙连接的细胞间相互作用]

[Intercellular interactions through gap junctions in embryonic stem cells].

作者信息

Sharovskaia Iu Iu

出版信息

Biofizika. 2011 Jan-Feb;56(1):99-104.

Abstract

The article deals with the last research project of Levon Mikhailovich Chailakhyan devoted to the role of local intercellular interactions in maintaining the pluripotency of embryonic stem cells and in the processes of their spontaneous multitissue differentiation. For performing the project, Levon Mikhailovich organized in 2008 a group of researchers from the Vavilov Institute of General Genetics of the Russian Academy of Sciences and Belozersky Research Institute of Physicochemical Biology of Lomonosov Moscow State University. In the last month of his life, Levon Mikhailovich wrote an article concerned with the first results of the work. At present the work on the project is being continued.

摘要

这篇文章论述了列翁·米哈伊洛维奇·柴拉赫扬的最后一个研究项目,该项目致力于研究局部细胞间相互作用在维持胚胎干细胞多能性以及其自发多组织分化过程中的作用。为开展该项目,列翁·米哈伊洛维奇在2008年组织了一批来自俄罗斯科学院瓦维洛夫普通遗传学研究所和莫斯科国立大学罗蒙诺索夫物理化学生物学别洛泽尔斯基研究所的研究人员。在他生命的最后一个月,列翁·米哈伊洛维奇撰写了一篇关于该工作初步成果的文章。目前该项目的工作仍在继续。

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