Pellegrini Santiago
Instituto de Investigaciones Médicas, Consejo Nacional de Investigaciones Científicas y Técnicas, Combatientes de Malvinas 3150, 1428 Ciudad Autónoma de Buenos Aires, Argentina.
Behav Processes. 2011 Jun;87(2):190-6. doi: 10.1016/j.beproc.2011.03.002. Epub 2011 Apr 1.
Paradoxical extinction effects in the conditioned consummatory behavior of rodents have remained largely elusive. Here, appetitive flavor conditioning was studied to determine if a paradoxical magnitude of reinforcement extinction effect (MREE) can occur in the consummatory behavior of mice. During acquisition training of two experiments with factorial design, animals received daily access to either 32% or 4% sucrose solution, and goal tracking time was measured in one-minute bins. In Experiment 1 the solutions were flavored with either 5% or 0.5% almond essence and in Experiment 2 with 2% almond essence, but combined with continuous or partial schedules of reinforcement. During extinction tests of Experiment 1 and 2, water flavored with 0.5% or 2% almond was presented, respectively. Consummatory performance decreased more abruptly during the initial portion of the extinction sessions after training with 32% as compared to 4% sucrose solution. Furthermore, when given a choice test after extinction training (Experiment 2), animals trained with 32% sucrose, preferred the flavored solution, but animals trained with 4% preferred the unflavored solution. These results are interpreted as indicative of the occurrence of a paradoxical MREE in conditioned consummatory behaviors.
啮齿动物条件性进食行为中的反常消退效应在很大程度上仍不为人所知。在此，研究了食欲性味觉条件作用，以确定在小鼠的进食行为中是否会出现反常的强化消退效应（MREE）。在两个采用析因设计的实验的习得训练期间，动物每天可获取32%或4%的蔗糖溶液，并以一分钟的时间段测量目标追踪时间。在实验1中，溶液分别用5%或0.5%的杏仁香精调味，在实验2中用2%的杏仁香精调味，但结合了连续或部分强化程序。在实验1和实验2的消退测试期间，分别呈现用0.5%或2%杏仁调味的水。与4%蔗糖溶液训练相比，用32%蔗糖溶液训练后，在消退阶段的初始部分，进食表现下降得更为突然。此外，在消退训练后进行选择测试时（实验2），用32%蔗糖训练的动物更喜欢有味道的溶液，而用4%蔗糖训练的动物更喜欢无味道的溶液。这些结果被解释为表明在条件性进食行为中出现了反常的MREE。
