Grape J, Frosch P
Hautklinik, Klinikum Dortmund gGmbH.
Hautarzt. 2011 Aug;62(8):618-20. doi: 10.1007/s00105-010-2121-6.
Cutaneous drug reactions can take many forms. In rare cases these reactions can occur along the lines of Blaschko. A 60-year-old patient received lenalidomide in 3-weeks-cycles for the treatment of a plasmocytoma. After four months of treatment, red papules appeared on the extremities and the trunk following the lines of Blaschko. The lesions nearly disappeared during drug-free intervals and appeared with renewed intensity after restart of a therapy cycle.
皮肤药物反应可表现为多种形式。在罕见情况下，这些反应可沿Blaschko线出现。一名60岁患者接受来那度胺治疗浆细胞瘤，治疗周期为3周。治疗四个月后，沿Blaschko线在四肢和躯干出现红色丘疹。在停药期间皮损几乎消失，重新开始治疗周期后又再次出现且症状加重。
