Munksgaard E C, Knudsen B, Thomsen K
Institut for odontologisk materialelaere & teknologi, Kobenhavns Tandlaegehojskole.
Tandlaegebladet. 1990 May;94(7):270-4.
Eight dentists and one dental assistant have developed allergic contact dermatitis caused by exposure to (di)methacrylates, especially those found in resins, in dentin bonding agents, in rebasement and in prosthetic materials. The eczema is characterized by its location on the first, second and third finger of the left hand showing redness, desquamation, fissuring and excoriations. Patch testing with various test substances revealed positive reactions towards EGDMA in eight cases. It is suggested that this reaction was a cross-reaction and that the sensibilization was caused by MMA, TEGDMA, HEMA and/or BUDMA. One of the eight dentists had to give up practising.
八名牙医和一名牙科助理因接触（二）甲基丙烯酸酯类物质，尤其是树脂、牙本质粘结剂、垫底材料和修复材料中含有的此类物质，而患上了过敏性接触性皮炎。湿疹的特征是位于左手的食指、中指和无名指，表现为发红、脱皮、开裂和擦伤。对多种测试物质进行斑贴试验后发现，八例患者对乙二醇二甲基丙烯酸酯（EGDMA）呈阳性反应。据推测，这种反应是交叉反应，致敏是由甲基丙烯酸甲酯（MMA）、三乙二醇二甲基丙烯酸酯（TEGDMA）、甲基丙烯酸羟乙酯（HEMA）和/或双甲基丙烯酸丁二醇酯（BUDMA）引起的。八名牙医中有一人不得不放弃行医。
