Department of Nephrology and Hypertension, Western Galilee Hospital, Nahariya, Israel.
Ren Fail. 2011;33(5):544-7. doi: 10.3109/0886022X.2011.569107. Epub 2011 Mar 29.
Metamizole sodium, a nonsteroidal anti-inflammatory drug, has been widely used in the last 100 years. Its efficacy as an analgesic and antipyretic is unquestionable. Only few cases of acute kidney injury (AKI) induced by metamizole sodium were reported in the medical literature. We report 11 adult patients with AKI that resulted from metamizole sodium ingestion. The data suggest a good prognosis in these cases of AKI. Renal biopsies, corticosteroids treatment, or renal replacement therapy seem to be not necessary. Hydration was sufficient to ensure spontaneous recovery.
甲灭酸（扑热息痛），一种非甾体抗炎药，在过去的 100 年中被广泛使用。其作为一种镇痛药和解热药的疗效是不容置疑的。只有少数几例因甲灭酸引起的急性肾损伤（AKI）的病例在医学文献中报道。我们报告了 11 例因服用甲灭酸而导致 AKI 的成年患者。数据表明，这些 AKI 病例的预后良好。肾活检、皮质类固醇治疗或肾脏替代治疗似乎是不必要的。水化治疗足以确保自发恢复。
