Mirastschijski Ursula, Altmann Silke, Lenz-Scharf Olivia, Muschke Petra, Schneider Wolfgang
Department of Plastic, Hand and Reconstructive Surgery, Hannover Medical School, Hannover.
J Plast Surg Hand Surg. 2012 Feb;46(1):45-8. doi: 10.3109/02844310902957728. Epub 2010 Sep 6.
Syndromes with focal overgrowth are sporadic diseases and comprise Proteus syndrome and congenital lipomatous overgrowth, vascular malformations, and epidermal naevi (CLOVE) syndrome, and isolated hemihyperplasia. We describe 3 children classified according to standard criteria with dysregulated growth of various tissues that was excised, together with excess toes, and tumours. Correct classification facilitates diagnosis and operations. Interdisciplinary treatment and follow-up are recommended to prevent disfiguration.
伴有局灶性过度生长的综合征是散发性疾病，包括普洛透斯综合征、先天性脂肪瘤性过度生长、血管畸形和表皮痣（CLOVE）综合征以及孤立性半身肥大。我们描述了3名根据标准标准分类的儿童，他们存在各种组织生长失调的情况，这些组织已被切除，同时还伴有多余的脚趾和肿瘤。正确分类有助于诊断和手术。建议进行多学科治疗和随访以防止毁容。
