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掌骨骨髓水肿为主的甲-厚皮骨病:POPP 的“顿挫型”?

Onycho-pachydermatit with extensive bone marrow edema predominant in the metacarpals: a "forme fruste" of POPP?

机构信息

Department of Radiology, Gulhane Military Medical Academy, Gn.Tevfik Saglam Cad., 06018, Etlik-Ankara, Turkey.

出版信息

Rheumatol Int. 2012 May;32(5):1449-52. doi: 10.1007/s00296-011-1914-y. Epub 2011 Mar 30.

DOI:10.1007/s00296-011-1914-y
PMID:21448639
Abstract

Psoriatic onycho-pachydermo-osteo/periostitis (POPP) syndrome is a rare form of psoriatic arthritis with a combination of (i) psoriatic onychodystrophy, (ii) connective tissue thickening, and (iii) periostitis of the distal phalanges. The treatment of the condition has generally been reported to be unsatisfactory with the traditional regimes. Here, we describe a case whom we believe is one presentation of POPP with extensive bone marrow edema of metacarpal bones without distinctive periostitis.

摘要

银屑病甲肥厚性骨/骨膜炎(POPP)综合征是一种罕见的银屑病关节炎形式,具有(i)银屑病甲营养不良,(ii)结缔组织增厚,和(iii)末节指骨骨膜炎的组合。该疾病的治疗通常被报道为传统疗法不满意。在这里,我们描述了一例我们认为是 POPP 的表现,掌骨有广泛的骨髓水肿,而没有明显的骨膜炎。

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本文引用的文献

1
Psoriatic onychopachydermoperiostitis (POPP): a perplexing case study.银屑病性甲厚皮性骨膜病(POPP):一个令人困惑的病例研究。
J Am Podiatr Med Assoc. 2009 Mar-Apr;99(2):140-3. doi: 10.7547/0980140.
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The nail as a musculoskeletal appendage--implications for an improved understanding of the link between psoriasis and arthritis.作为肌肉骨骼附属器的指甲——对增进理解银屑病与关节炎之间联系的启示。
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Detailed analysis of contrast-enhanced MRI of hands and wrists in patients with psoriatic arthritis.
银屑病关节炎患者手部和腕部对比增强磁共振成像的详细分析。
Skeletal Radiol. 2008 May;37(5):433-42. doi: 10.1007/s00256-008-0451-6. Epub 2008 Feb 20.
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Psoriatic onycho-pachydermo-periostitis successfully treated with low-dose methotrexate.低剂量甲氨蝶呤成功治疗银屑病性甲厚皮性骨膜炎
Med Sci Monit. 2006 Apr;12(4):CS27-30. Epub 2006 Mar 28.
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Magnetic resonance imaging in psoriatic arthritis: a review of the literature.银屑病关节炎的磁共振成像:文献综述
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Successful treatment of psoriatic onycho-pachydermo periostitis (POPP) with adalimumab.阿达木单抗成功治疗银屑病性甲厚皮性骨膜病(POPP)。
Arthritis Rheum. 2005 Jan;52(1):280-2. doi: 10.1002/art.20763.
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Magnetic resonance imaging of psoriatic arthritis: insight from traditional and three-dimensional analysis.银屑病关节炎的磁共振成像:传统分析与三维分析的见解
Curr Rheumatol Rep. 2004 Aug;6(4):317-21. doi: 10.1007/s11926-004-0045-9.
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[Psoriasiform onychopachydermoperiostitis of the large toes: the OP3GO syndrome].[拇趾的银屑病样甲厚皮性骨膜骨炎:OP3GO综合征]
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Overuse edema in the bone marrow of the hand: demonstration with MRI.手部骨髓过度使用性水肿:MRI表现
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10
Psoriatic onycho-pachydermo-periostitis. A variant of psoriatic distal interphalangeal arthritis?银屑病性甲厚皮骨膜炎。银屑病性远端指间关节炎的一种变异型?
Arch Dermatol. 1996 Feb;132(2):176-80.