Molinatti G M, Biffignandi P
Istituto di Medicina Interna dell'Università degli Studi di Torino.
Ann Ital Med Int. 1990 Jan-Mar;5(1):39-47.
This review aims at focusing current pathogenetic theories on female idiopathic hirsutism. Glandular hormonal synthesis, plasma transport of androgenic hormones, and cutaneous metabolism and utilization of testosterone are discussed in detail. The Authors then propose some therapeutic strategies: antiandrogen drugs are discussed with special reference to cyproterone acetate and spironolactone.
本综述旨在聚焦当前关于女性特发性多毛症的发病机制理论。详细讨论了腺性激素合成、雄激素的血浆转运以及睾酮的皮肤代谢与利用。作者随后提出了一些治疗策略:特别提及醋酸环丙孕酮和螺内酯,对抗雄激素药物进行了讨论。