Department of Cardiology, Al Mowasat University Hospital, Damascus, Syria.
J Cardiovasc Med (Hagerstown). 2011 May;12(5):340-2. doi: 10.2459/JCM.0b013e328343e9e0.
Resistant hypertension is defined as failure to achieve goal blood pressure (BP) when a patient adheres to the maximum tolerated doses of three antihypertensive drugs including a diuretic. Although the exact prevalence of resistant hypertension is currently unknown, indirect evidence from population studies and clinical trials suggests that it is a relatively common clinical problem. Exclusion of preparations that contribute to true BP treatment resistance, such as NSAIDs and certain herbs, is also important. In Syria and other middle-eastern countries, licorice juice ingestion is considered as a distinct reason for resistant hypertension.
耐药性高血压定义为患者坚持服用最大耐受剂量的三种降压药物（包括利尿剂）仍无法达到目标血压时的血压控制失败。尽管耐药性高血压的确切患病率目前尚不清楚，但来自人群研究和临床试验的间接证据表明，这是一个相对常见的临床问题。排除导致真正血压治疗抵抗的制剂也很重要，如 NSAIDs 和某些草药。在叙利亚和其他中东国家，甘草汁的摄入被认为是耐药性高血压的一个明显原因。
