Otolaryngology-Head and Neck Surgery Department, University Hospital of Modena, Modena, Italy.
Otol Neurotol. 2011 Jun;32(4):626-31. doi: 10.1097/MAO.0b013e3182171007.
The aim of the present study is to document and analyze the ossicular chain preservation rate in patients affected by acquired primary cholesteatoma with epitympanic involvement and with preoperative intact ossicular chain.
A retrospective case series in a tertiary university referral center.
From January 2006 to February 2010, at the Otolaryngology Department of the University Hospital of Modena, 68 patients affected by acquired primary cholesteatoma with attic involvement underwent exclusive endoscopic transcanal tympanoplasty. In April 2010, we performed a retrospective chart and video review of these patients. Patients in whom the ossicular chain was found to be intact and not involved by the pathology at the beginning of the operation were included in the study. A cholesteatoma staging was introduced based on tympanic subsite involvement by pathology.
Out of 68 patients affected by acquired primary cholesteatoma and who underwent exclusive endoscopic transcanal tympanoplasty, 23 had intraoperative integrity of the ossicular chain (17 male and 6 female subjects; mean age, 40 yr) and were included in the study. An inverse correlation was found between number of subsites involved and chain preservation (Spearman rank correlation coefficient, r = -1; p = 0.017). Medial attic involvement was the factor that most negatively influenced the likelihood of chain preservation.
Middle ear endoscopic techniques may increase the likelihood of ossicular chain preservation during cholesteatoma surgery. Medial attic involvement and a high number of subsites involved represent the most significant negative factors for chain preservation. The rate of residual disease requires more thorough evaluation in the future to validate the results.
本研究旨在记录和分析患有原发性上鼓室胆脂瘤并伴有术前完整听骨链的患者的听骨链保留率。
这是一家三级大学转诊中心的回顾性病例系列研究。
2006 年 1 月至 2010 年 2 月,摩德纳大学医院耳鼻喉科对 68 例原发性上鼓室胆脂瘤患者行单纯内镜经耳道鼓室成形术。2010 年 4 月,我们对这些患者进行了回顾性图表和视频复查。在手术开始时发现听骨链完整且不受病理影响的患者被纳入研究。根据病理累及的鼓膜隐窝部位引入胆脂瘤分期。
在 68 例接受单纯内镜经耳道鼓室成形术的原发性上鼓室胆脂瘤患者中,有 23 例术中听骨链完整(17 例男性和 6 例女性;平均年龄 40 岁),并被纳入研究。受累鼓室隐窝数量与听骨链保留率呈负相关(Spearman 秩相关系数,r=-1;p=0.017)。内侧鼓室隐窝受累是影响听骨链保留的最不利因素。
中耳内镜技术可提高胆脂瘤手术中听骨链保留的可能性。内侧鼓室隐窝受累和受累鼓室隐窝数量多是影响听骨链保留的最显著负因素。残留疾病的发生率需要进一步更彻底的评估,以验证研究结果。