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非分泌型多发性骨髓瘤复发为骨髓外肝浆细胞瘤。

Non-secretory multiple myeloma relapsing as extramedullary liver plasmacytomas.

机构信息

Serviço de Hematologia, Hospital Santo António dos Capuchos, 1169-050 Lisboa, Portugal.

出版信息

J Gastrointestin Liver Dis. 2011 Mar;20(1):81-3.

PMID:21451803
Abstract

We report a case of a 58-year-old woman with a true non secretory multiple myeloma of the producer type relapsing after many lines of therapy including the novel anti-myeloma drugs, which eventually relapsed as extramedullary liver plasmacytomas manifesting as a fatal acute cholestatic hepatitis. Due to the aggressiveness of this disease, new therapeutic modalities are necessary.

摘要

我们报告了一例 58 岁女性的真性非分泌型多发性骨髓瘤,该患者在接受了包括新型抗骨髓瘤药物在内的多种治疗方案后复发,最终复发为髓外肝浆细胞瘤,表现为致命性急性胆汁淤积性肝炎。由于这种疾病的侵袭性,需要新的治疗方法。

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1
Non-secretory multiple myeloma relapsing as extramedullary liver plasmacytomas.非分泌型多发性骨髓瘤复发为骨髓外肝浆细胞瘤。
J Gastrointestin Liver Dis. 2011 Mar;20(1):81-3.
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Severe acute cholestatic hepatitis by infiltration of monoclonal plasma cells in multiple myeloma.多发性骨髓瘤中克隆性浆细胞浸润所致的严重急性胆汁淤积性肝炎
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[Relapse of multiple myeloma in extramedullary sites].[多发性骨髓瘤髓外部位复发]
Harefuah. 1993 May 2;124(9):539-41, 600.
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[Multiple myeloma causing obstructive jaundice by extramedullary plasmacytoma after Bence Jones protein loss--an autopsy case report].[本-周蛋白丢失后髓外浆细胞瘤致多发性骨髓瘤引起梗阻性黄疸——1例尸检病例报告]
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Intrasellar plasmacytoma: an unusual presentation of multiple myeloma.鞍内浆细胞瘤:多发性骨髓瘤的一种不寻常表现。
Acta Neurochir (Wien). 2008 Sep;150(9):921-4; discussion 924. doi: 10.1007/s00701-008-0012-8. Epub 2008 Aug 23.
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Extramedullary plasmacytoma of the breast.乳腺髓外浆细胞瘤
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CD38-targeted Immuno-PET of Multiple Myeloma: From Xenograft Models to First-in-Human Imaging.CD38 靶向免疫 PET 多发性骨髓瘤:从异种移植模型到首例人体成像。
Radiology. 2020 Jun;295(3):606-615. doi: 10.1148/radiol.2020192621. Epub 2020 Apr 7.
2
Asymptomatic Multiple Myeloma Presenting as a Nodular Hepatic Lesion: A Case Report and Review of the Literature.以结节性肝病变为表现的无症状多发性骨髓瘤:一例报告并文献复习
Ochsner J. 2015 Winter;15(4):457-67.
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Nonsecretory multiple myeloma presenting as an intestinal tumor.表现为肠道肿瘤的非分泌型多发性骨髓瘤
Case Rep Hematol. 2015;2015:818715. doi: 10.1155/2015/818715. Epub 2015 Apr 16.
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Imaging features of extramedullary, relapsed, and refractory multiple myeloma involving the liver across treatment with cyclophosphamide, lenalidomide, bortezomib, and dexamethasone.环磷酰胺、来那度胺、硼替佐米及地塞米松治疗过程中累及肝脏的髓外、复发及难治性多发性骨髓瘤的影像特征
J Clin Oncol. 2012 Jul 10;30(20):e175-9. doi: 10.1200/JCO.2011.41.1413. Epub 2012 Jun 11.