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聚(2,3-二氨基萘)微球作为一种新型荧光增强核酸检测猝灭剂。

Poly(2,3-diaminonaphthalene) microspheres as a novel quencher for fluorescence-enhanced nucleic acid detection.

机构信息

State Key Lab of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022 Jilin, China.

出版信息

Analyst. 2011 Jun 7;136(11):2221-4. doi: 10.1039/c0an00944j. Epub 2011 Mar 31.

Abstract

In this Communication, we report on the first preparation of conjugation polymer poly(2,3-diaminonaphthalene) (PDAN) microspheres via chemical oxidation polymerization of 2,3-diaminonaphthalene (DAN) monomers by ammonium persulfate (APS) at room temperature. We further demonstrate the use of PDAN microspheres as a novel quencher for fluorescence-enhanced nucleic acid detection.

摘要

在本通讯中,我们报告了通过室温下过硫酸铵 (APS) 对 2,3-二氨基萘 (DAN) 单体的化学氧化聚合首次制备共轭聚合物聚 (2,3-二氨基萘) (PDAN) 微球。我们进一步展示了 PDAN 微球作为一种新型荧光增强核酸检测淬灭剂的用途。

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