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[2009年7月至9月,留尼汪岛圣皮埃尔急诊科甲型H1N1流感大流行病毒感染暴发]

[Outbreak of influenza pandemic virus A(H1N1) 2009 infections in the Emergency Department, Saint-Pierre, Réunion Island, July-September 2009].

作者信息

Staikowsky F, Vanhecke C, D'Andréa C, Souab A, Rakotoson R, Michault A

机构信息

Service des Urgences, SMUR, UHCD, CHR de la Réunion, site Sud, avenue François-Mitterrand, F-97410, Saint Pierre, Île de la Réunion, France.

出版信息

Bull Soc Pathol Exot. 2011 May;104(2):125-34. doi: 10.1007/s13149-011-0144-6. Epub 2011 Mar 30.

DOI:10.1007/s13149-011-0144-6
PMID:21451954
Abstract

A new H1N1 virus originating from swine recently emerged as the first influenza pandemic of the 21st century. On July 3, 2009, this new influenza A(H1N1) virus (S-OIV) of swine origins was identified in Réunion Island, a French overseas department located in the southern hemisphere. The present study describes the characteristics of the epidemic from July 3 to September 30, 2009. Among the 479 patients included in our study (236 males, 37.3 ± 19.0 years), 255 (53.2%) were reported to have comorbidities or risk factors (RF) for complications. Complications occurred in 160 patients (33.4%). The most common complications were bronchial hyperreactivity (52.7%), pneumonia (32.1%), and decompensation caused by comorbidity (17.9%). 111 patients (23.2%) required hospitalization. Patients aged 65 and over, accounted for 11.9% of all patients, 32.4% of hospitalized patients and 22.5% of complicated S-OIV infections. Regardless of age, comorbidity and/or RF were reported in 80.0% of complicated S-OIV infections and 91.0% of hospitalized patients. Recommendations for surveillance, prevention and policy for persons with RF, particularly respiratory disease, are justified. However, the absence of risk factors did not prevent the occurrence of complications, present in 14.3% of the cases.

摘要

一种源自猪的新型H1N1病毒最近成为21世纪的首例流感大流行。2009年7月3日,这种源自猪的新型甲型H1N1病毒(S-OIV)在位于南半球的法国海外省留尼汪岛被发现。本研究描述了2009年7月3日至9月30日该疫情的特征。在我们研究纳入的479例患者中(男性236例,年龄37.3±19.0岁),255例(53.2%)报告有并发症的合并症或危险因素(RF)。160例患者(33.4%)出现了并发症。最常见的并发症是支气管高反应性(52.7%)、肺炎(32.1%)以及合并症导致的失代偿(17.9%)。111例患者(23.2%)需要住院治疗。65岁及以上的患者占所有患者的11.9%,占住院患者的32.4%,占S-OIV复杂感染患者的22.5%。无论年龄如何,80.0%的S-OIV复杂感染患者以及91.0%的住院患者报告有合并症和/或RF。对有RF的人群,尤其是呼吸系统疾病患者进行监测、预防及制定政策的建议是合理的。然而,没有危险因素并不能阻止并发症的发生,14.3%的病例出现了并发症。

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