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本文引用的文献

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In vivo breast sound-speed imaging with ultrasound tomography.利用超声断层扫描进行体内乳房声速成像。
Ultrasound Med Biol. 2009 Oct;35(10):1615-28. doi: 10.1016/j.ultrasmedbio.2009.05.011. Epub 2009 Aug 3.
2
Propagation and backpropagation for ultrasonic wavefront design.用于超声波前波阵面设计的传播与反向传播
IEEE Trans Ultrason Ferroelectr Freq Control. 1997;44(1):1-13. doi: 10.1109/58.585184.
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Detection of breast cancer with ultrasound tomography: first results with the Computed Ultrasound Risk Evaluation (CURE) prototype.超声断层扫描检测乳腺癌:计算机超声风险评估(CURE)原型的初步结果。
Med Phys. 2007 Feb;34(2):773-85. doi: 10.1118/1.2432161.
4
Development of ultrasound tomography for breast imaging: technical assessment.用于乳腺成像的超声断层扫描技术的发展:技术评估
Med Phys. 2005 May;32(5):1375-86. doi: 10.1118/1.1897463.
5
Solid breast nodules: use of sonography to distinguish between benign and malignant lesions.实性乳腺结节:利用超声鉴别良恶性病变
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Breast imaging in coronal planes with simultaneous pulse echo and transmission ultrasound.采用同步脉冲回波和透射超声技术进行冠状面乳腺成像。
Science. 1981 Dec 4;214(4525):1141-3. doi: 10.1126/science.7302585.

变声声速和衰减 Kirchhoff 偏移的改进及其在介质声成像中的应用和在乳房层析成像中的应用。

Modification of Kirchhoff migration with variable sound speed and attenuation for acoustic imaging of media and application to tomographic imaging of the breast.

机构信息

Department of Physics and Astronomy, Wayne State University, Detroit, Michigan 48201, USA.

出版信息

Med Phys. 2011 Feb;38(2):998-1007. doi: 10.1118/1.3539552.

DOI:10.1118/1.3539552
PMID:21452737
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3045413/
Abstract

PURPOSE

To explore the feasibility of improving cross-sectional reflection imaging of the breast using refractive and attenuation corrections derived from ultrasound tomography data.

METHODS

The authors have adapted the planar Kirchhoff migration method, commonly used in geophysics to reconstruct reflection images, for use in ultrasound tomography imaging of the breast. Furthermore, the authors extended this method to allow for refractive and attenuative corrections. Using clinical data obtained with a breast imaging prototype, the authors applied this method to generate cross-sectional reflection images of the breast that were corrected using known distributions of sound speed and attenuation obtained from the same data.

RESULTS

A comparison of images reconstructed with and without the corrections showed varying degrees of improvement. The sound speed correction resulted in sharpening of detail, while the attenuation correction reduced the central darkening caused by path length dependent losses. The improvements appeared to be greatest when dense tissue was involved and the least for fatty tissue. These results are consistent with the expectation that denser tissues lead to both greater refractive effects and greater attenuation.

CONCLUSIONS

Although conventional ultrasound techniques use time-gain control to correct for attenuation gradients, these corrections lead to artifacts because the true attenuation distribution is not known. The use of constant sound speed leads to additional artifacts that arise from not knowing the sound speed distribution. The authors show that in the context of ultrasound tomography, it is possible to construct reflection images of the breast that correct for inhomogeneous distributions of both sound speed and attenuation.

摘要

目的

探索利用超声层析成像数据导出的折射和衰减校正来改善乳房横截面反射成像的可行性。

方法

作者改编了平面 Kirchhoff 偏移法,该方法常用于地球物理学中的反射成像重建,用于乳房超声层析成像。此外,作者扩展了该方法以允许进行折射和衰减校正。使用乳房成像原型获得的临床数据,作者应用该方法生成乳房的横截面反射图像,并使用从同一数据获得的已知声速和衰减分布对其进行校正。

结果

对校正前后重建的图像进行比较,显示出不同程度的改善。声速校正导致细节更加清晰锐利,而衰减校正减少了由于路径长度相关损失引起的中央暗化。当涉及致密组织时,改善似乎最大,而对于脂肪组织则最小。这些结果与预期一致,即密度较高的组织会导致更大的折射效应和更大的衰减。

结论

尽管传统的超声技术使用时程增益控制来校正衰减梯度,但这些校正会导致伪影,因为不知道真实的衰减分布。使用恒定的声速会导致由于不知道声速分布而产生的其他伪影。作者表明,在超声层析成像的背景下,可以构建乳房的反射图像,对声速和衰减的不均匀分布进行校正。