Department of Psychiatry and Clinical Psychobiology, School of Psychology, University of Barcelona, Spain.
Chronobiol Int. 2011 Apr;28(3):248-57. doi: 10.3109/07420528.2011.553018.
Few studies have focused on the influence of circadian typology on drug use, and none has considered the use of illegal drugs and hazardous alcohol consumption. This study analyzes the influence of circadian typology on several types of drug consumption (habitual or sporadic), hangover symptoms (past 12 mos), and, more specifically, hazardous alcohol consumption of young adults. Five hundred seventeen university students (173 males), between 17 and 30 yrs of age, answered the Composite Scale of Morningness (CSM), the Alcohol Use Disorders Identification Test (AUDIT), and a self-referred questionnaire on drug consumption during the previous month and on the prevalence of different hangover symptoms during the previous year. Our results confirm a higher prevalence of consumption of addictive substances, both legal (nicotine and cola drinks) and illegal (cannabis and ecstasy), in evening- compared to morning- and neither-type subjects (p < .001 in all cases). Evening-type subjects also obtained a higher total score on the AUDIT (p < .001) and showed a greater prevalence in the subscales of potential alcohol problems (p < .02), as well as more frequent different hangover symptoms (learning difficulties, thirst, tiredness, headaches, sensorial hypersensitivity, anxiety, and irritability; p < .04 in all cases) compared with morning- and neither-type subjects, except for sensorial hypersensitivity and anxiety, for which the evening-type did not differ from the neither-type. Our results provide substantial evidence that the evening circadian typology is a risk factor for the development of drug consumption and that it should be taken into account both in preventive and treatment approaches. Moreover, the data regarding hazardous alcohol use and hangover symptoms emphasize the need to include circadian typology in future studies on the pattern of heavy episodic drinking.
这项研究分析了昼夜节律类型对几种类型的药物使用(习惯性或偶发性)、宿醉症状(过去 12 个月)的影响,更具体地说,还分析了其对年轻人危险饮酒行为的影响。517 名年龄在 17 至 30 岁之间的大学生(173 名男性)回答了综合晨型量表(CSM)、酒精使用障碍识别测试(AUDIT),以及过去一个月内自我报告的药物使用情况和过去一年中不同宿醉症状的流行情况问卷。我们的结果证实,与晨型和非典型个体相比,晚上型个体更有可能使用成瘾物质,包括合法物质(尼古丁和可乐饮料)和非法物质(大麻和摇头丸)(所有情况下 p < 0.001)。晚上型个体的 AUDIT 总分也更高(p < 0.001),并且在潜在酒精问题的亚量表中表现出更高的流行率(p < 0.02),以及更频繁的不同宿醉症状(学习困难、口渴、疲劳、头痛、感官过敏、焦虑和易怒;所有情况下 p < 0.04),与晨型和非典型个体相比,除了感官过敏和焦虑,晚上型个体与非典型个体没有差异。我们的结果提供了充分的证据表明,夜间昼夜节律类型是药物使用发展的一个危险因素,在预防和治疗方法中都应考虑到这一点。此外,关于危险饮酒行为和宿醉症状的数据强调了在关于重度间歇性饮酒模式的未来研究中纳入昼夜节律类型的必要性。