Department of Neurology, University of Colorado, Denver Health and Hospitals, Denver, CO, USA.
High Alt Med Biol. 2011 Spring;12(1):13-9. doi: 10.1089/ham.2010.1071.
Counseling patients who suffer first-time or break- through seizures can be difficult, particularly when controllable external factors may be contributing to the lowering of their seizure threshold. High altitude as a potential trigger for seizures is a common question in our epilepsy clinics in Colorado, and this article reviews the existing anecdotal literature, presents our local experience with high altitude seizures (HAS), offers possible mechanisms to explain how high altitude may trigger seizures, and suggests an initial work-up and prophylactic strategies for future high altitude exposures.
对首次发作或突破发作的患者进行咨询可能具有挑战性，尤其是当可控制的外部因素可能导致其发作阈值降低时。高海拔地区作为癫痫发作的潜在触发因素是我们在科罗拉多州癫痫诊所中常见的问题，本文综述了现有的轶事文献，介绍了我们在高海拔地区癫痫发作方面的本地经验，提出了可能的机制来解释高海拔地区如何引发癫痫发作，并为未来的高海拔暴露提供了初步的检查和预防策略。
