Department of Dermatology, Dokuz Eylül University, İzmir, Turkey.
J Dermatol. 2011 Jul;38(7):707-10. doi: 10.1111/j.1346-8138.2011.01220.x. Epub 2011 Mar 31.
Lichen planus pemphigoides (LPP) is a rare and controversial disease. It is characterized clinically by tense bullae arising both on lichen planus papules and on uninvolved skin, histologically by the demonstration of subepidermal bullae and by linear deposits of immunoglobulin G and C3 along the basement membrane zone on immunofluorescence of peribullous skin. Some authors consider LPP as the combination of lichen planus and bullous pemphigoid. Others think that it most likely encompasses a heterogeneous group of subepidermal autoimmune blistering disorders occurring in association with lichen planus. We present a child case that supports the heterogeneous condition of this disease triggered by varicella.
类天疱疮(LPP)是一种罕见且有争议的疾病。其临床特征为在扁平苔藓丘疹和未受累皮肤上出现紧张性大疱,组织学上表现为表皮下水疱,以及在围绕大疱的皮肤免疫荧光检查中免疫球蛋白 G 和 C3 沿基底膜带呈线性沉积。一些作者认为 LPP 是扁平苔藓和大疱性类天疱疮的组合。另一些人则认为,它很可能包含一组异质性的表皮下自身免疫性水疱性疾病,与扁平苔藓有关。我们提出了一个儿童病例,支持了这种疾病的异质性,其由水痘引发。