Liu Song-Yan, Han Xue-Mei, Yan Ya-Yun, Sun Bo-Jian, Chang Ying
Department of Neurology, China-Japan Union Hospital, Jilin University, Changchun 130033, China.
Chin J Traumatol. 2011 Apr 1;14(2):100-3.
To observe the quality of life in patients with post-traumatic epilepsy and discuss the influencing factors.
We assessed 105 patients with post-traumatic epilepsy and 100 healthy people as control using Quality of Life Scale-31 (QOL-31), Self-rating Depressing Scale (SDS) and Self-rating Anxiety Scale (SAS), and conducted retrospective analysis on the depression, anxiety, site of trauma, control of seizure, EEG and therapeutic compliance.
Patients with post-traumatic epilepsy scored much lower than the control group on QOL-31 (P less than 0.01), but higher than the control group on SDS and SAS (P less than 0.01). Multiple regression analysis indicated that major influencing factors on the quality of life were anxiety, therapeutic compliance, depression, poor control of epileptic seizure and site of trauma.
The quality of life in patients with post-traumatic epilepsy has significantly declined. Doctors should pay attention to psychological and mental problems of patients with epilepsy, such as depression and anxiety, enhancing therapeutic compliance and controlling epileptic seizure, which are the keys to improving prognosis.
观察创伤后癫痫患者的生活质量并探讨其影响因素。
采用生活质量量表-31(QOL-31)、自评抑郁量表(SDS)和自评焦虑量表(SAS)对105例创伤后癫痫患者及100例健康对照者进行评估,并对抑郁、焦虑、创伤部位、癫痫控制情况、脑电图及治疗依从性进行回顾性分析。
创伤后癫痫患者的QOL-31评分显著低于对照组(P<0.01),但SDS和SAS评分高于对照组(P<0.01)。多元回归分析表明,影响生活质量的主要因素为焦虑、治疗依从性、抑郁、癫痫控制不佳及创伤部位。
创伤后癫痫患者的生活质量显著下降。医生应关注癫痫患者的心理和精神问题,如抑郁和焦虑,提高治疗依从性并控制癫痫发作,这是改善预后的关键。