Théron J, Courthéoux P, Alachkar F, Maiza D
Service de Neuroradiologie et Radiologie Interventionnelle, CHU, Caen.
J Mal Vasc. 1990;15(3):245-56.
Two techniques of cerebral revascularization have been developed: angioplasty of the brachiocephalic vessels (204 cases) and local intra-arterial fibrinolysis in the carotid region (26 cases). Angioplasty appears to be the treatment of choice for inflammatory and atherosclerotic stenoses of the main trunks arising from the aortic arch (82 cases). Stenoses of the origin of the vertebral artery are not often ulcerated and may also be treated by angioplasty (42 cases) as long as the stenosis has been recognized as the cause of vertebral insufficiency symptoms. Among the stenoses of the carotid bifurcation, recurrent postsurgical ones are rather easily treated by angioplasty, particularly when they are recognized early by Doppler examination. Postsurgical and inflammatory stenoses do not require cerebral protection during angioplasty. Conversely, cerebral protection is mandatory for treatment of atherosclerotic stenoses because of the risk of embolic detachment of particles in to brain circulation. A new triple coaxial catheter system has been designed which seems so far to be very efficient. Local intra-arterial fibrinolysis in the carotid region is selected on the basis of clinical signs, the delay after onset and results of CT and complete cerebral angiographic workup. A classification into three topographic groups is proposed. The group at highest risk of post-fibrinolysis hemorrhage is the one with occlusion of the lenticulostriate arteries. It would seem hazardous to undertake fibrinolysis in a patient of this group unless it can be started no later than 4 or 5 hours after clinical onset. Rapid transportation of stroke patients is recommended so that CT and complete arteriography may be performed before deciding whether to use fibrinolytics.
头臂血管成形术(204例)和颈动脉区域局部动脉内纤维蛋白溶解术(26例)。血管成形术似乎是治疗主动脉弓主干炎性和动脉粥样硬化性狭窄的首选方法(82例)。椎动脉起始部狭窄通常不会发生溃疡,只要已确认狭窄是椎动脉供血不足症状的原因,也可通过血管成形术治疗(42例)。在颈动脉分叉处狭窄中,术后复发性狭窄通过血管成形术相当容易治疗,尤其是在通过多普勒检查早期发现时。术后和炎性狭窄在血管成形术期间不需要脑保护。相反,由于存在颗粒栓塞进入脑循环的风险,动脉粥样硬化性狭窄的治疗必须进行脑保护。已经设计了一种新的三同轴导管系统,到目前为止似乎非常有效。颈动脉区域局部动脉内纤维蛋白溶解术是根据临床体征、发病后的延迟时间以及CT和全脑血管造影检查结果来选择的。提出了一种分为三个地形学组的分类方法。纤维蛋白溶解术后出血风险最高的组是豆纹动脉闭塞的组。除非在临床发病后不迟于4或5小时开始,否则对该组患者进行纤维蛋白溶解术似乎很危险。建议对中风患者进行快速转运,以便在决定是否使用纤维蛋白溶解剂之前进行CT和全动脉造影检查。