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膀胱外翻中膀胱颈重建术的应用

The use of bladder neck reconstruction in bladder exstrophy.

作者信息

Borer Joseph G

机构信息

Department of Surgery (Urology), Harvard Medical School and Assistant in Urology, Children's Hospital Boston, Boston, MA 02115, USA.

出版信息

Semin Pediatr Surg. 2011 May;20(2):91-6. doi: 10.1053/j.sempedsurg.2010.12.003.

Abstract

A major goal of bladder exstrophy (BE) management is achieving urinary continence, most commonly with surgical bladder neck reconstruction (BNR). This is a report of outcome of BNR after complete primary repair of exstrophy (CPRE). At our institution, patient history, ultrasound, cystogram (VCUG) and urodynamic study (UDS) were performed during a prospective evaluation of patients with BE. Dry interval of >3 hours was used as the definition of continence and dry interval <1-hour incontinence. Bladder capacity was measured at VCUG and/or UDS. UDS was also used to assess bladder compliance. From 1994 to 2010, we cared for 47 BE patients (31 male, 15 female) after CPRE. For patients ≥3 years after CPRE, BNR was performed in 9 of 22 (41%) male and 3 of 11 (27%) female patients. Mean age at BNR was 6.3 and 5.9 years for male and female patients, respectively. The mean (±SD) bladder capacity pre-BNR was 104.8 (±20.4 mL). There was a significant increase in capacity from pre-BNR to ≥1.5 years post-BNR (P = 0.013) and from <1.5 and ≥1.5 years post-BNR (P = 0.002). In conclusion, most patients with BE require BNR after CPRE. The need for BNR is more common in male patients.

摘要

膀胱外翻(BE)治疗的一个主要目标是实现尿失禁,最常见的方法是进行外科膀胱颈重建术(BNR)。这是一篇关于膀胱外翻一期完全修复(CPRE)后进行BNR的结果报告。在我们机构,对BE患者进行前瞻性评估时,收集了患者病史、超声、膀胱造影(VCUG)和尿动力学研究(UDS)的数据。以干间期>3小时作为尿失禁的定义,干间期<1小时为尿失禁。在VCUG和/或UDS检查时测量膀胱容量。UDS还用于评估膀胱顺应性。1994年至2010年,我们对47例CPRE后的BE患者(31例男性,15例女性)进行了治疗。对于CPRE后≥3年的患者,22例男性患者中有9例(41%)、11例女性患者中有3例(27%)进行了BNR。男性和女性患者进行BNR时的平均年龄分别为6.3岁和5.9岁。BNR术前的平均(±标准差)膀胱容量为104.8(±20.4 mL)。从BNR术前到BNR术后≥1.5年,容量有显著增加(P = 0.013),从BNR术后<1.5年到≥1.5年也有显著增加(P = 0.002)。总之,大多数BE患者在CPRE后需要进行BNR。BNR在男性患者中更为常见。

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