炎症性肠病相关性坏疽性脓皮病：1998 年至 2009 年 Mater 卫生服务成人医院的经验。
Pyoderma gangrenosum in inflammatory bowel disease: the experience at Mater Health Services' Adult Hospital 1998-2009.
机构信息
The University of Queensland, Australia.
出版信息
J Crohns Colitis. 2011 Apr;5(2):148-51. doi: 10.1016/j.crohns.2010.10.006. Epub 2011 Feb 22.
BACKGROUND AND AIMS
Pyoderma gangrenosum (PG) is a neutrophilic dermatosis often associated with inflammatory bowel disease (IBD). The literature has suggested that PG-IBD is usually associated with ulcerative colitis.
METHODS
We reviewed the PG-IBD cases at the Mater Health Services' Adult Hospital in Brisbane between 1998 and 2009 through assessment of a comprehensive web database of IBD patients and verification of chart information of PG-IBD cases.
RESULTS
PG-IBD at Mater was associated with clinically mild colonic IBD, with erythema nodosum, and with female sex. All PG-IBD responded eventually to increased immunomodulatory therapy.
CONCLUSION
We discuss why PG-IBD is associated with clinically mild colonic IBD be it ulcerative colitis, Crohn's or indeterminate colitis.
背景与目的
坏疽性脓皮病（PG）是一种中性粒细胞性皮肤病，常与炎症性肠病（IBD）有关。文献表明，PG-IBD 通常与溃疡性结肠炎相关。
方法
我们通过评估布里斯班 Mater 健康服务成人医院的 IBD 患者综合网络数据库并验证 PG-IBD 病例的图表信息，回顾了 1998 年至 2009 年期间在该医院发生的 PG-IBD 病例。
结果
Mater 的 PG-IBD 与临床轻度结肠 IBD、结节性红斑和女性性别相关。所有 PG-IBD 最终均对增加免疫调节治疗有反应。
结论
我们讨论了为什么 PG-IBD 与临床轻度结肠 IBD（无论是溃疡性结肠炎、克罗恩病还是不确定结肠炎）相关。
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