Department of Neurology, Samsung Medical Center, College of Medicine, Sungkyunkwan University, Seoul, Korea.
J Stroke Cerebrovasc Dis. 2012 Nov;21(8):904.e1-2. doi: 10.1016/j.jstrokecerebrovasdis.2011.02.014. Epub 2011 Mar 30.
Intravascular lymphomatosis (IVL) is known to affect both hemispheres of the brain and manifests clinically as seizures or dementia. To our knowledge, there have been no cases in which acute hemispheric dysfunction is manifested in IVL. We present a 54-year-old man who showed steroid responsive acute hemispheric dysfunction. A technetium 99m-ethyl cysteinate dimer single-photon emission computed tomographic scan of the brain revealed hypoperfusion in the right hemisphere. The bone marrow biopsy specimen confirmed malignant lymphoid cells in vessels, which suggested IVL. Our case signifies the diversity of clinical manifestations in IVL.
血管内淋巴瘤（IVL）已知会影响大脑的两个半球，并表现为癫痫发作或痴呆。据我们所知，IVL 中尚未出现过急性半球功能障碍的病例。我们报告了一例 54 岁男性，表现为类固醇反应性急性半球功能障碍。脑 99m 锝-乙硫氨酸二聚体单光子发射计算机断层扫描显示右半球灌注不足。骨髓活检标本证实血管中有恶性淋巴样细胞，提示 IVL。我们的病例表明 IVL 的临床表现具有多样性。
